sterile

adjective

ster·​ile ˈster-əl 

chiefly British

-ˌī(-ə)l 

1

a

: failing to bear or incapable of producing fruit or spores

b

: failing to produce or incapable of producing offspring

a sterile hybrid

c

: incapable of germinating

sterile spores

d

of a flower : neither perfect nor pistillate

2

a

: unproductive of vegetation

a sterile arid region

b

: free from living organisms and especially pathogenic microorganisms

a sterile syringe

c

: lacking in stimulating emotional or intellectual quality : lifeless

a sterile work of art

sterilely

ˈster-ə(l)-lē 

chiefly British -ˌī(-ə)(l)-lē

adverb

sterility

stə-ˈri-lə-tē 

noun

Synonyms of sterile

• barren
• sterilized

Examples of sterile in a Sentence

a sterile dressing for a wound

sterile couples sometimes choose to adopt needy children

Recent Examples on the Web

The second stories house supplies of the metals, films, and components needed, as well as a very substantial set of HVAC equipment to keep the processes sterile, dust-free, and at the right temperature. — John Voelcker, The Verge, 12 Oct. 2026

Right now yeast fermentation is the standard method of producing heme (as leghemoglobin), but the sterile environment and industrial equipment necessary for manufacturing can be pricey. — Lila Magbilang, Scientific American, 12 Oct. 2026

Dozens of people died, and investigators later found severe safety lapses in the pharmacy’s production of sterile drugs. — Alana Semuels, Time, 7 Oct. 2026

Asha Indoor/Outdoor Area Rug If your patio is feeling sterile, layering in accents like an outdoor rug is the key to achieving a cozier vibe. — Audrey Lee, Architectural Digest, 6 Oct. 2026

Word History

Etymology

Middle English steryle, from Latin sterilis; akin to Goth stairo barren animal, Sanskrit starī sterile cow

First Known Use

15th century, in the meaning defined at sense 1a

Phrases Containing sterile

• male-sterile
• self-sterile

Rhymes for sterile

• beryl
• feral
• karel
• peril
• seral
• sterol
• carbaryl
• glyceryl
• imperil
• foraminiferal
• tocopherol

Kids Definition

sterile

adjective

ster·​ile ˈster-əl 

1

: not able to produce fruit, crops, or offspring : not fertile

sterile soil

2

: free from microscopic living things and especially germs (as bacteria and viruses)

a sterile dressing for a wound

sterility

stə-ˈril-ət-ē 

noun

Medical Definition

sterile

adjective

ster·​ile

ˈster-əl, chiefly British -ˌīl

1

: failing to produce or incapable of producing offspring

a sterile hybrid

compare infertile

2

: free from living organisms and especially microorganisms

a sterile syringe

a sterile cyst

sterilely

-əl-(l)ē 

adverb

sterility

stə-ˈril-ət-ē 

noun

plural sterilities