serotonin

noun

se·​ro·​to·​nin ˌsir-ə-ˈtō-nən 

ˌser-

: a phenolic amine neurotransmitter C₁₀H₁₂N₂O that is a powerful vasoconstrictor and is found especially in the brain, blood serum, and gastric mucous membrane of mammals

Examples of serotonin in a Sentence

Recent Examples on the Web

The folate in avocado also aids in controlling serotonin and dopamine levels, which can decrease risk of depression. —Sheah Rarback, Miami Herald, 31 July 2025

Oats have plenty of complex carbohydrates and tryptophan, which helps make and support serotonin and energy regulation. —Dr. Samanta Dall’agnese, CNBC, 18 July 2025

According to Stengel, it is assumed that the effect is achieved via modulation of inflammatory processes, nerve activity, and the regulation of stress hormones such as cortisol and neurotransmitters such as serotonin and dopamine—all of which happens along the gut-brain axis. —Desireé Oostland, Vogue, 17 July 2025

Additionally, watermelon contains vitamin B6, which is involved in making neurotransmitters like serotonin and dopamine, according to Mason. —Sherri Gordon, Health, 3 July 2025

Word History

Etymology

sero- + ton(ic) entry 2 or tone entry 1 + -in entry 1, probably after angiotonin, earlier name for angiotensin — more at angiotensin

Note: Term introduced by Maurice M. Rapport, Arda Alden Green and Irvine H. Page in "Crystalline serotonin," Science, vol. 108, Issue 2804 (September 24, 1948), pp. 329-330: "The general behavior of the crystalline substance is suggestive of its homogeneity. We would like provisionally to name it serotonin, which indicates that its source is serum and its activity is one of causing constriction."

First Known Use

1948, in the meaning defined above

Phrases Containing serotonin

• selective serotonin reuptake inhibitor

Rhymes for serotonin

• calcitonin
• digitonin
• melatonin
• kronen
• onan
• phonon
• ronin
• santonin

Medical Definition

serotonin

noun

se·​ro·​to·​nin ˌsir-ə-ˈtō-nən  ˌser- 

: a phenolic amine neurotransmitter C₁₀H₁₂N₂O that is a powerful vasoconstrictor and is found especially in the brain, blood serum, and gastric mucous membrane of mammals

called also 5-HT, 5-hydroxytryptamine