an·​gio·​ten·​sin | \ ˌan-jē-ō-ˈten(t)-sən How to pronounce angiotensin (audio) \

Definition of angiotensin

: either of two forms of a kinin of which one has marked vasoconstrictive action also : a synthetic amide derivative of the physiologically active form used to treat some forms of hypotension

Examples of angiotensin in a Sentence

Recent Examples on the Web Millions of blood-pressure pills known as angiotensin II receptor blockers were recalled beginning in July 2018 after it was found their active ingredients were contaminated with NDMA as a byproduct of the manufacturing process. Anna Edney,, "Five Drugmakers Are Asked to Recall Tainted Diabetes Drug," 30 May 2020 The ape form of the angiotensin-converting enzyme 2 receptor that the new coronavirus uses to enter cells is identical to the human one, making it likely that apes can be infected, according to an 11 April preprint on bioRxiv. Ann Gibbons, Science | AAAS, "Primatologists work to keep great apes safe from coronavirus," 1 May 2020 The spike protein attaches to a receptor on human cells called angiotensin-converting enzyme 2. Kai Kupferschmidt, Science | AAAS, "How the pandemic made this virologist an unlikely cult figure," 28 Apr. 2020 Research has shown estrogen may have an effect on a protein known as angiotensin-converting enzyme 2 (ACE2), for example. Roni Caryn Rabin, New York Times, "Can Estrogen and Other Sex Hormones Help Men Survive Covid-19?," 27 Apr. 2020 Research has shown estrogen may have an effect on a protein known as angiotensin-converting enzyme 2 (ACE2), for example. Roni Caryn Rabin,, "Can estrogen and other sex hormones help men survive COVID-19?," 27 Apr. 2020 In a healthy person, the ACE2 receptor chops up two forms of a protein called angiotensin to keep blood pressure stable, among other things. Kate Sheridan, STAT, "The coronavirus sneaks into cells through a key receptor. Could targeting it lead to a treatment?," 10 Apr. 2020 The virus seems to attack the body by attaching to a binding receptor called angiotensin-converting enzyme-2, or ACE-2. Jan Hoffman, New York Times, "Smokers and Vapers May Be at Greater Risk for Covid-19," 9 Apr. 2020 The concern stems from the fact that SARS and the new coronavirus enter cells by latching on to a protein called angiotensin-converting enzyme 2, or ACE2 for short. National Geographic, "THE BEST OF NATIONAL GEOGRAPHIC DELIVERED TO YOUR INBOX," 24 Mar. 2020

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'angiotensin.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of angiotensin

1958, in the meaning defined above

History and Etymology for angiotensin

angiotonin, an earlier name for the substance (from angio- + Greek tónos "stretching, strain, tension," alluding to its pressor effect + -in entry 1) + hypertensin, a synonymous name, from hypertens(ion) + -in entry 1, after Spanish hipertensina — more at tone entry 1

Note: The term angiotonin was introduced by the American physiologist Irvine H. Page (1901-91) and biochemist Oscar M. Helmer in "A crystalline pressor substance (angiotonin) resulting from the reaction between renin and renin activator," Journal of Experimental Medicine, vol. 71, No. 1 (January 1, 1940), pp. 29-42. The etymology is stated explicitly: "For this substance we suggest the name 'angiotonin' [Greek ἀγγεῖον, blood vessel, + τόνος (τείνω), strain]" (p. 29). Spanish hipertensina was introduced by the Argentine physiologist Eduardo Braun-Menéndez (1903-59) and coworkers in "La sustancia hipertensora de la sangre del riñón isquemiado," Revista de la Sociedad Argentina de Biología, vol. 15 (1939), pp. 420-25. Page and Braun-Menéndez later agreed to merge the two synonymous names into angiotensin; see "Suggested Revision of Nomenclature—Angiotensin," Science, vol. 127, Issue 3292 (January 31, 1958), p. 242.

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The first known use of angiotensin was in 1958

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Cite this Entry

“Angiotensin.” Dictionary, Merriam-Webster, Accessed 25 Nov. 2020.

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More Definitions for angiotensin


an·​gio·​ten·​sin | \ ˌan-jē-ō-ˈten(t)-sən How to pronounce angiotensin (audio) \

Medical Definition of angiotensin

1 : either of two forms of a kinin of which one has marked physiological activity and the other is its physiologically inactive precursor especially : angiotensin ii
2 : a synthetic amide derivative of angiotensin II used to treat some forms of hypotension

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