serotonin

noun

se·​ro·​to·​nin ˌsir-ə-ˈtō-nən How to pronounce serotonin (audio)
ˌser-
: a phenolic amine neurotransmitter C10H12N2O that is a powerful vasoconstrictor and is found especially in the brain, blood serum, and gastric mucous membrane of mammals

Examples of serotonin in a Sentence

Recent Examples on the Web
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Research has shown that music can boost the brain's production of dopamine and serotonin, and also reduce cortisol levels. Jack Beresford, MSNBC Newsweek, 29 June 2025 To assess the starting point, a very thorough biomarker examination happens after check in; the results range from body mass index, strength and exercise recovery capacity to brain serotonin level, heart rate response to challenge and insulin resistance among many others. Laurie Werner, Forbes.com, 25 June 2025 Research suggests that low serotonin levels during the luteal phase may explain the mood changes that come with PMS. Sherri Gordon, Health, 11 June 2025 That includes serotonin, melatonin and micronutrients like magnesium, vitamin B6 and folate, which also help the body to produce melatonin. Malaka Gharib, NPR, 19 May 2025 See All Example Sentences for serotonin

Word History

Etymology

sero- + ton(ic) entry 2 or tone entry 1 + -in entry 1, probably after angiotonin, earlier name for angiotensin — more at angiotensin

Note: Term introduced by Maurice M. Rapport, Arda Alden Green and Irvine H. Page in "Crystalline serotonin," Science, vol. 108, Issue 2804 (September 24, 1948), pp. 329-330: "The general behavior of the crystalline substance is suggestive of its homogeneity. We would like provisionally to name it serotonin, which indicates that its source is serum and its activity is one of causing constriction."

First Known Use

1948, in the meaning defined above

Time Traveler
The first known use of serotonin was in 1948

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Cite this Entry

“Serotonin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/serotonin. Accessed 14 Jul. 2025.

Medical Definition

serotonin

noun
se·​ro·​to·​nin ˌsir-ə-ˈtō-nən How to pronounce serotonin (audio) ˌser- How to pronounce serotonin (audio)
: a phenolic amine neurotransmitter C10H12N2O that is a powerful vasoconstrictor and is found especially in the brain, blood serum, and gastric mucous membrane of mammals

called also 5-HT, 5-hydroxytryptamine

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