se·​ro·​neg·​a·​tive ˌsir-ō-ˈne-gə-tiv How to pronounce seronegative (audio)
: having or being a negative serum reaction especially in a test for the presence of an antibody
seronegativity noun

Example Sentences

Recent Examples on the Web Before the fourth booster, all the seronegative participants had geometric mean titers (GMT) of omicron neutralizing antibodies at around 300. Beth Mole, Ars Technica, 8 June 2022 For example, as described by a publication in EClinical Medicine 5% of 698 people in Israel remained seronegative despite having tested positive for the Covid-19 coronavirus. Bruce Y. Lee, Forbes, 5 Sep. 2021 There was other evidence the antibody cocktail helped these seronegative patients. Matthew Herper, STAT, 17 June 2021 The second dose brought a boost in antibodies for the seronegative group compared to the seropositive group. Chris Smith, BGR, 11 Mar. 2021 In the Regeneron data, the most dramatic drops in SARS-CoV-2 were seen in seronegative patients who had the highest levels of virus at the trial’s start. Jon Cohen, Science | AAAS, 30 Sep. 2020 For patients given a placebo, the seropositive group had a median time to alleviation of symptoms of 7 days, compared to 13 days for seronegative patients. NBC News, 29 Sep. 2020 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'seronegative.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

Word History


sero- + negative entry 1

First Known Use

1927, in the meaning defined above

Time Traveler
The first known use of seronegative was in 1927

Dictionary Entries Near seronegative

Cite this Entry

“Seronegative.” Dictionary, Merriam-Webster, Accessed 6 Dec. 2022.

Medical Definition



se·​ro·​neg·​a·​tive -ˈneg-ə-tiv How to pronounce seronegative (audio)
: having or being a negative serum reaction especially in a test for the presence of an antibody
early seronegative syphilis
a seronegative patient
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