selective estrogen receptor modulator

noun

: any of a class of drugs (such as raloxifene or tamoxifen) that bind with estrogen receptors (as of the breast, uterus, or bone) and act as agonists to enhance estrogen activity in some tissues and as antagonists to inhibit estrogen activity in other tissues
… a selective estrogen receptor modulator, or SERM, has estrogenlike effects on bone but acts like an antiestrogen in breast and uterine tissue, thus protecting against hormone-stimulated cancers …Jane E. Brody

called also SERM

Word History

First Known Use

1994, in the meaning defined above

Time Traveler
The first known use of selective estrogen receptor modulator was in 1994

Dictionary Entries Near selective estrogen receptor modulator

selective cutting

selective estrogen receptor modulator

selective flotation

Cite this Entry

“Selective estrogen receptor modulator.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/selective%20estrogen%20receptor%20modulator. Accessed 27 Jan. 2023.

Medical Definition

selective estrogen receptor modulator

noun
: any of a class of drugs (as raloxifene or tamoxifen) that bind with estrogen receptors (as of the breast, uterus, or bone) and act as agonists to enhance estrogen activity in some tissues and as antagonists to inhibit estrogen activity in other tissues
… a selective estrogen receptor modulator, or SERM, has estrogenlike effects on bone but acts like an antiestrogen in breast and uterine tissue, thus protecting against hormone-stimulated cancers …Jane E. Brody, The New York Times
Selective estrogen receptor modulators, a newer group of agents, maximize the beneficial effects of estrogen on bone and minimize its deleterious effects on the breast and endometrium.Charles Marwick, The Journal of the American Medical Association

called also SERM

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