Definition of raloxifene
: a drug used orally in the form of its hydrochloride C28H27NO4S·HCl as prophylaxis against osteoporosis after menopause
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In particular, two drugs—called tamoxifen and raloxifene—can block estrogen in the breast cells, lowering the risk of developing breast cancer by about 40%, according to the American Cancer Society.
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Origin and Etymology of raloxifene
ral- (of unknown origin) + -oxifene, alteration of -oxifen (as in tamoxifen)
Medical Dictionary
medical Definition of raloxifene
: a drug used orally in the form of its hydrochloride C28H27NO4S·HCl to prevent and treat osteoporosis after menopause and to reduce the risk of developing invasive breast cancer
Note:
Raloxifene binds to the estrogen receptors of cells and is in a class of drugs known as selective estrogen receptor modulators. It is marketed under the trademark Evista.
- Drugs like raloxifene target estrogen receptors to preserve bone mass.
- —Claudia Kalb, Newsweek, 22 July 2002
- … raloxifene operates as an estrogen agonist in bone but as an antagonist in the breast and uterus.
- —Gideon A. Rodan et al., Science, 1 Sept. 2000
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