raloxifene

noun

ral·ox·i·fene | \ˌra-ˈläk-sə-ˌfēn

Definition of raloxifene

: a drug used orally in the form of its hydrochloride C₂₈H₂₇NO₄S·HCl as prophylaxis against osteoporosis after menopause

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In particular, two drugs—called tamoxifen and raloxifene—can block estrogen in the breast cells, lowering the risk of developing breast cancer by about 40%, according to the American Cancer Society. — Maria Masters, Health.com, "5 Steps You Can Take to Reduce Your Risk of Breast Cancer Recurrence," 17 Oct. 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'raloxifene.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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The first known use of raloxifene was in 1993

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raloxifene

noun

ral·ox·i·fene | \ˌral-ˈäk-sə-ˌfēn

Medical Definition of raloxifene

: a drug used orally in the form of its hydrochloride C₂₈H₂₇NO₄S·HCl to prevent and treat osteoporosis after menopause and to reduce the risk of developing invasive breast cancer

Note: Raloxifene binds to the estrogen receptors of cells and is in a class of drugs known as selective estrogen receptor modulators. It is marketed under the trademark Evista.

Drugs like raloxifene target estrogen receptors to preserve bone mass.— Claudia Kalb, Newsweek, 22 July 2002 … raloxifene operates as an estrogen agonist in bone but as an antagonist in the breast and uterus.— Gideon A. Rodan et al., Science, 1 Sept. 2000