tamoxifen

noun
ta·​mox·​i·​fen | \ tə-ˈmäk-sə-ˌfen How to pronounce tamoxifen (audio) \

Definition of tamoxifen

: an estrogen antagonist C26H29NO used in the form of its citrate especially to treat postmenopausal breast cancer

Examples of tamoxifen in a Sentence

Recent Examples on the Web These are tumors that do not carry receptors for estrogen, progesterone, or human epidermal growth factor, typically targeted by such drugs as Herceptin or tamoxifen. Adam Feuerstein, STAT, "Immunomedics wins FDA approval for new drug to treat aggressive form of breast cancer," 22 Apr. 2020 All participants were given standard hormone therapy (an aromatase inhibitor or tamoxifen) as well as a medication that shuts down the ovaries' production of estrogen. Samantha Lauriello, Health.com, "A New Breast Cancer Treatment Can Extend the Lives of Younger Patients, Study Finds," 4 June 2019 All of the women were given standard hormonal therapy -- an aromatase inhibitor or tamoxifen -- plus a medication that shuts down the ovaries' production of estrogen. Amy Norton, CBS News, "Newer drug extends lives of young breast cancer patients, study finds," 3 June 2019 Hormone therapy with the drug tamoxifen is also common. Korin Miller, SELF, "What Are My Options for Ovarian Cancer Treatment?," 13 Dec. 2018 Phyllis Laccetti, a participant in the study, took the hormonal therapy tamoxifen alone for five years after having a mastectomy in 2007 to treat her breast cancer, even though her doctor’s initial recommendation was to also receive chemotherapy. Peter Loftus, WSJ, "Doctors Suggest Less Chemo, Surgery for Some Cancer Treatments," 3 June 2018 Generally, after surgery, such patients receive endocrine therapy, such as tamoxifen, which is designed to block the cancer-spurring effects of hormones. Laurie Mcginley, Washington Post, "Most women with a common type of early-stage breast cancer can skip chemo, a new report finds," 3 June 2018 Generally, after surgery, such patients receive endocrine therapy, such as tamoxifen, which is designed to block the cancer-spurring effects of hormones. Laurie Mcginley, BostonGlobe.com, "Study finds some with early-stage breast cancer can skip chemotherapy," 3 June 2018 And a Tufts University study, published earlier this year, showed that soy consumption isn’t problematic for women who currently have breast cancer and doesn’t make cancer treatment drugs like tamoxifen less effective. Marygrace Taylor, Good Housekeeping, "Is Soy Good Or Bad For You? We Have The Science-Backed Answer.," 17 May 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'tamoxifen.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of tamoxifen

1972, in the meaning defined above

History and Etymology for tamoxifen

probably by recombination & alteration of trans-, oxy, and clomiphene

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Time Traveler for tamoxifen

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The first known use of tamoxifen was in 1972

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Cite this Entry

“Tamoxifen.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/tamoxifen. Accessed 18 Jan. 2021.

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More Definitions for tamoxifen

tamoxifen

noun
ta·​mox·​i·​fen | \ ta-ˈmäk-si-ˌfen How to pronounce tamoxifen (audio) \

Medical Definition of tamoxifen

: a selective estrogen receptor modulator that acts as an estrogen antagonist in breast tissue and is administered orally in the form of its citrate C26H29NO·C6H8O7 especially to treat breast cancer or reduce the risk of its development or reoccurrence — see nolvadex

More from Merriam-Webster on tamoxifen

Britannica.com: Encyclopedia article about tamoxifen

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