quadrivalent

1 of 2

adjective

quad·​ri·​va·​lent ˌkwä-drə-ˈvā-lənt How to pronounce quadrivalent (audio)
in sense 2
kwä-ˈdri-və-lənt How to pronounce quadrivalent (audio)
1
2
: composed of four homologous chromosomes synapsed in meiotic prophase

quadrivalent

2 of 2

noun

: a quadrivalent chromosomal group

Examples of quadrivalent in a Sentence

Recent Examples on the Web
Adjective
But the makers of quadrivalent vaccines largely only have licenses to make quadrivalent vaccines—not trivalent ones. Beth Mole, Ars Technica, 5 Oct. 2023 A number of the previous trivalent licenses manufacturers of quadrivalent vaccines held still exist but have been discontinued, Weir told the committee. Helen Branswell, STAT, 5 Oct. 2023 For the majority of those aged 6 months and older, the CDC recommends receiving the standard quadrivalent flu vaccine, which protects against four different strains of the virus. Mary Kekatos, ABC News, 22 Nov. 2023 After years of work, the first quadrivalent shots began to roll out in 2012. Helen Branswell, STAT, 5 Oct. 2023 The flu shots currently used in the United States employ a quadrivalent formulation. Helen Branswell, STAT, 29 Sep. 2023 Both lab and rapid-flu tests show more than 70 percent of patients are testing positive for Influenza B, which historically is less serious than Influenza A and the B strain is covered by this year's quadrivalent flu shot. Bill Hanna, star-telegram, 2 Mar. 2018 Both the trivalent and quadrivalent vaccines given this year protect against the B strain that seems to be popping up most often, but there could still be other strains out there. Kate Morgan, The Cut, 4 Apr. 2018 Typically, trivalent formulations include two A strains and one B strain, and quadrivalent formulations add a second B strain. Susan Scutti, CNN, 21 June 2017
Noun
That could effectively open up one of the seats in the vaccines, dropping them next season from quadrivalent formulations – targeting four different antigens in a single shot – to trivalent. Alexander Tin, CBS News, 29 Feb. 2024 Then the quadrivalent Gardasil was administered until 2023, when the nonavalent Gardasil 9 was introduced. Annalisa Merelli, STAT, 25 Jan. 2024 Flu vaccines for the 2023-2024 season in the Northern Hemisphere are out now (with a B/Yamagata component in quadrivalent formulations)—far too late for a retool. Beth Mole, Ars Technica, 5 Oct. 2023 Not all countries use quadrivalent vaccines; the four-in-one shots are mainly used in affluent countries. Helen Branswell, STAT, 5 Oct. 2023 The trial compared the immune response generated by a new pentavalent, or 5-in-1, vaccine called NmCV-5 against that of the licensed quadrivalent, or 4-in-1, MenACWY-D vaccine. Laura Baisas, Popular Science, 24 May 2023 For example, getting a quadrivalent flu shot at CVS can cost $95, while a regular flu shot is $50. Carla Delgado, Verywell Health, 24 Jan. 2023 The investigational vaccine is a two-in-one combination of Novavax’s Covid-19 vaccine and its quadrivalent flu vaccine candidate. Jacqueline Howard, CNN, 10 Nov. 2022 This year's quadrivalent formulation of the flu shot contains an H3N2 strain, which is dominant in the U.S. right now. Kristen Jordan Shamus, Detroit Free Press, 6 Nov. 2022

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'quadrivalent.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

Etymology

Adjective

International Scientific Vocabulary

First Known Use

Adjective

1865, in the meaning defined at sense 1

Noun

1923, in the meaning defined above

Time Traveler
The first known use of quadrivalent was in 1865

Dictionary Entries Near quadrivalent

Cite this Entry

“Quadrivalent.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/quadrivalent. Accessed 12 Apr. 2024.

Medical Definition

quadrivalent

1 of 2 adjective
quad·​ri·​va·​lent
ˌkwäd-rə-ˈvā-lənt, in sense 2 kwä-ˈdriv-ə-lənt
1
2
: composed of four homologous chromosomes synapsed in meiotic prophase

quadrivalent

2 of 2 noun
: a quadrivalent chromosomal group
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