psy·​cho·​ac·​tive | \ ˌsī-kō-ˈak-tiv How to pronounce psychoactive (audio) \

Definition of psychoactive

: affecting the mind or behavior psychoactive drugs

Examples of psychoactive in a Sentence

Recent Examples on the Web Former University of Oregon pole vaulter Cole Walsh has completed a three-month suspension after testing positive in January for THC, the main psychoactive constituent of cannabis, marijuana, and/or hashish. oregonlive, "Former Oregon Duck pole vaulter Cole Walsh serves suspension after positive test for cannabis," 1 June 2020 Huffman wasn’t looking to create a marijuana-like high; his research focused on endocannabinoid receptors, which in addition to being responsible for cannabis’s psychoactive effects, is also related to inflammatory pain. Rudy Sanchez,, "‘Synthetic marijuana’ is a dangerous misnomer that people need to stop using," 12 Nov. 2019 If high and middle school pupils are caught consuming alcohol or drugs or vaping THC -- the psychoactive substance in marijuana -- the punishment is a 10-day out-of-school suspension and police citation for a first offense. Bob Sandrick, cleveland, "Strongsville schools increase penalties for vaping, consider educational alternatives," 29 Oct. 2019 Inside the bag — emblazoned with a logo featuring the San Gabriel mountains — was tea infused with Cannabidiol, or CBD, which is not the non-psychoactive ingredient in cannabis plants. Lila Seidman, Glendale News-Press, "Local ‘witch doctor’ aims to cure what ails you at his Montrose CBD store," 27 Sep. 2019 The Stanley brothers, marijuana growers in Colorado, were crossbreeding a strain of marijuana high in CBD and low in THC, its psychoactive ingredient. Mallory Simon, CNN, "Charlotte Figi, the girl who inspired a CBD movement, has died at age 13," 8 Apr. 2020 The two cannabis plants look and smell alike, but hemp has a far lower concentration of THC, or tetrahydrocannabinol, the psychoactive component, than marijuana., "In the nearly two years since New York state began widely authorizing farmers to grow hemp, farmers like Rogers have had to go to unusual lengths to protect their crops because so many people — from thieves to law enforcement officials — mistake hemp for marijuana.," 4 Dec. 2019 Toxicology results for a woman who died in February suggested she was killed by an excess amount of THC, the primary psychoactive component of weed, the coroner, Christy Montegut, told the New Orleans Advocate. Marion Renault, Popular Science, "Can you overdose on weed?," 21 June 2019 He has reportedly been accused of testing positive for the psychoactive component in marijuana, THC, according to the Fort-Worth Star-Telegram, a violation of his probation. Ashley Boucher,, "'Affluenza Teen' Ethan Couch Arrested in Texas After Allegedly Violating Probation Again," 3 Jan. 2020

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'psychoactive.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

See More

First Known Use of psychoactive

1959, in the meaning defined above

Keep scrolling for more

Learn More about psychoactive

Time Traveler for psychoactive

Time Traveler

The first known use of psychoactive was in 1959

See more words from the same year

Statistics for psychoactive

Last Updated

21 Jun 2020

Cite this Entry

“Psychoactive.” Dictionary, Merriam-Webster, Accessed 4 Jul. 2020.

Keep scrolling for more

More Definitions for psychoactive


psy·​cho·​ac·​tive | \ ˌsī-kō-ˈak-tiv How to pronounce psychoactive (audio) \

Medical Definition of psychoactive

: affecting the mind or behavior psychoactive drugs THC is the principal psychoactive ingredient in marijuana

More from Merriam-Webster on psychoactive

Rhyming Dictionary: Words that rhyme with psychoactive

Comments on psychoactive

What made you want to look up psychoactive? Please tell us where you read or heard it (including the quote, if possible).


See Definitions and Examples »

Get Word of the Day daily email!

Test Your Vocabulary

A More Exception(al) Quiz

  • hot dog  hot dog  hot dog  hot dog cat
  • Which of the following words is not a synonym for ‘a young person’?
Spell It

Can you spell these 10 commonly misspelled words?

Bee Cubed

Test Your Knowledge - and learn some interesting things along the way.

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!