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psychoactive

adjective

psy·​cho·​ac·​tive ˌsī-kō-ˈak-tiv How to pronounce psychoactive (audio)
: affecting the mind or behavior
psychoactive drugs

Examples of psychoactive in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
But the funding bill that ended the federal government shutdown earlier this month included a provision cutting the amount of THC — the psychoactive compound responsible for a high — legally allowed in increasingly popular products such as drinks and gummies. Mary Ramsey, Charlotte Observer, 26 Nov. 2025 The treatment, which involves using the psychoactive substance from plants, Ibogaine, can treat traumatic brain injuries (TBIs), PTSD, anxiety and depression. Jackson Thompson, FOXNews.com, 25 Nov. 2025 With names like Mountain High, Buzzin' Breeze and Citrus Bliss, most of the drinks have only low doses of THC, the psychoactive ingredient in cannabis. Bill Chappell, NPR, 24 Nov. 2025 About five milligrams of that chemical, which is the main psychoactive component in marijuana, will make the occasional weed user feel a light buzz. Nicholas Florko, The Atlantic, 21 Nov. 2025 See All Example Sentences for psychoactive

Word History

First Known Use

1958, in the meaning defined above

Time Traveler
The first known use of psychoactive was in 1958

Browse Nearby Words

Cite this Entry

“Psychoactive.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/psychoactive. Accessed 29 Nov. 2025.

Kids Definition

psychoactive

adjective
psy·​cho·​ac·​tive ˌsī-kō-ˈak-tiv How to pronounce psychoactive (audio)
: affecting the mind or behavior
psychoactive drugs

Medical Definition

psychoactive

adjective
psy·​cho·​ac·​tive ˌsī-kō-ˈak-tiv How to pronounce psychoactive (audio)
: affecting the mind or behavior
psychoactive drugs
THC is the principal psychoactive ingredient in marijuana
Last Updated: - Updated example sentences
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