psy·​cho·​ac·​tive | \ ˌsī-kō-ˈak-tiv How to pronounce psychoactive (audio) \

Definition of psychoactive

: affecting the mind or behavior psychoactive drugs

Examples of psychoactive in a Sentence

Recent Examples on the Web This natural oil, derived from the Cannabis sativa or indica plants, can help calm your mind without the psychoactive effects found in tetrahydrocannabinol (THC)., "What's the Best CBD Oil for Anxiety? These 10 Products Earn High Marks," 14 May 2021 Neither the participants nor the researchers knew who had been given the psychoactive drug. Zoe Cormier, Scientific American, "MDMA Shows New Promise for Trauma, but the Drug Alone Is Not a Cure," 12 May 2021 Unlike the psychoactive chemical compound tetrahydrocannabinol (THC) found in marijuana, CBD products do not produce a high associated with cannabis. Rafael Guerrero,, "Warby Parker and Andrew’s Garden open in downtown Naperville, and more new businesses soon to follow," 8 May 2021 Hemp and marijuana are both cannabis plants, but hemp is historically an industrial plant — used to make textiles, biodegradable plastics, and more — and lacks the psychoactive effects of marijuana. Sophie Saint Thomas, Allure, "The 15 Best CBD Vape Pens," 20 Apr. 2021 In addition, a glass pipe recovered from the vehicle contained THC, the psychoactive component of marijuana, but no plant material, Giles told the court. Eric Levenson And Aaron Cooper, CNN, "Derek Chauvin's trial puts focus on George Floyd's suspected drug use as testimony continues," 8 Apr. 2021 As the pandemic brought uncertainty and anxiety, medical cannabis and non-psychoactive CBD sales saw a rise in Florida, according to data from the state’s Office of Medical Marijuana Use. Austen Erblat,, "Boca Raton lifted a ban on marijuana dispensaries. A year later, none has opened.," 23 Apr. 2021 THCa Non-psychoactive tetrahydrocannabinolic acid is present in raw cannabis and turns into more familiar THC when smoked. Los Angeles Times, "Overwhelmed by all the non-THC cannabis alternatives? Our weed guru breaks it down," 15 Apr. 2021 Is the name Martha Stewart enough to convince her to give the non-psychoactive cannabinoid a try? Nicola Fumo, Forbes, "20 Great Gift Ideas For Mother’s Day 2021," 12 Apr. 2021

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'psychoactive.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of psychoactive

1959, in the meaning defined above

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The first known use of psychoactive was in 1959

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Statistics for psychoactive

Last Updated

17 May 2021

Cite this Entry

“Psychoactive.” Dictionary, Merriam-Webster, Accessed 17 May. 2021.

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More Definitions for psychoactive


psy·​cho·​ac·​tive | \ ˌsī-kō-ˈak-tiv How to pronounce psychoactive (audio) \

Medical Definition of psychoactive

: affecting the mind or behavior psychoactive drugs THC is the principal psychoactive ingredient in marijuana

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