psy·​cho·​ac·​tive | \ ˌsī-kō-ˈak-tiv How to pronounce psychoactive (audio) \

Definition of psychoactive

: affecting the mind or behavior psychoactive drugs

Examples of psychoactive in a Sentence

Recent Examples on the Web Its core product was psilocybin, the psychoactive compound in magic mushrooms. Wired, 28 July 2022 Numerous studies have reported positive findings using psilocybin—the mushrooms' main psychoactive compound—for treating depression as well as smoking and alcohol addiction, and for reducing anxiety in the terminally ill. Simon Makin, Scientific American, 20 July 2022 Cannabis plants with broad-spectrum CBD include those found in industrial hemp, which contains the same chemicals as full-spectrum CBD but without the psychoactive component THC. The Salt Lake Tribune, 10 May 2022 The hospital confirmed each child had been exposed to tetrahydrocannabinol, the main psychoactive compound in cannabis. Andrew Mark Miller, Fox News, 16 Apr. 2022 One small cookie or gummy can contain multiple doses of THC, the main psychoactive component of marijuana. Andrea Petersen, WSJ, 8 Mar. 2022 Edibles avoid the harmful effects on the lungs from smoking pot, but may have more variable amounts of THC, the main psychoactive component in cannabis, and may take an hour or two to fully kick in, prompting some impatient users to take too much. Robert Mccoppin,, 20 Jan. 2022 As always, there is a risk that the product may contain THC, the main psychoactive component of cannabis. Dr. Keith Roach, oregonlive, 21 Dec. 2021 Anebulo Pharmaceuticals said Tuesday that a single dose of its experimental pill blunted the effects of THC, the psychoactive ingredient in marijuana, supporting further development of the medicine as a potential antidote for cannabis intoxication. Adam Feuerstein, STAT, 8 July 2022 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'psychoactive.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of psychoactive

1959, in the meaning defined above

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The first known use of psychoactive was in 1959

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Last Updated

9 Aug 2022

Cite this Entry

“Psychoactive.” Dictionary, Merriam-Webster, Accessed 11 Aug. 2022.

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More Definitions for psychoactive


psy·​cho·​ac·​tive | \ ˌsī-kō-ˈak-tiv How to pronounce psychoactive (audio) \

Medical Definition of psychoactive

: affecting the mind or behavior psychoactive drugs THC is the principal psychoactive ingredient in marijuana


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