psychoactive

adjective

psy·​cho·​ac·​tive ˌsī-kō-ˈak-tiv How to pronounce psychoactive (audio)
: affecting the mind or behavior
psychoactive drugs

Examples of psychoactive in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
In 2024, the Parliament of the Czech Republic adopted a draft law regulating synthetic cannabinoids and emerging psychoactive substances such as HHC and kratom. Dario Sabaghi, Forbes.com, 4 June 2025 One of the most psychoactive substances humans have ever ingested, in other words, is already everywhere around and inside us. Andy Greenberg, Wired News, 22 May 2025 Known for its soothing and uplifting effects, THC (tetrahydrocannabinol) is the primary psychoactive compound in cannabis. Matt Rozo, Mercury News, 29 May 2025 Fast-Acting Gummies Conventional cannabis edibles are notorious for often taking more than an hour or longer for the user to feel the psychoactive effects of THC. A.j. Herrington, Forbes.com, 27 May 2025 See All Example Sentences for psychoactive

Word History

First Known Use

1959, in the meaning defined above

Time Traveler
The first known use of psychoactive was in 1959

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Cite this Entry

“Psychoactive.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/psychoactive. Accessed 1 Jul. 2025.

Kids Definition

psychoactive

adjective
psy·​cho·​ac·​tive ˌsī-kō-ˈak-tiv How to pronounce psychoactive (audio)
: affecting the mind or behavior
psychoactive drugs

Medical Definition

psychoactive

adjective
psy·​cho·​ac·​tive ˌsī-kō-ˈak-tiv How to pronounce psychoactive (audio)
: affecting the mind or behavior
psychoactive drugs
THC is the principal psychoactive ingredient in marijuana
Last Updated: - Updated example sentences
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