proton pump inhibitor

noun

Updated on: 3 Apr 2018

Definition of proton pump inhibitor

: any of a group of drugs that inhibit the activity of pumps transporting hydrogen ions across cell membranes and are used to inhibit gastric acid secretion

Recent Examples of proton pump inhibitor from the Web

Researchers pooled data from eight observational studies and concluded that the risk of asthma in childhood increased by 34 percent when the mother used proton pump inhibitors and by 57 percent with the use of histamine-2 receptor antagonists.

— New York Times, "Antacids During Pregnancy Tied to Asthma in Children," 11 Jan. 2018
Statins interact with scores of them, including proton pump inhibitors (like Nexium), blood pressure and heart medications (like Plavix), and many antibiotics.

— paula span, New York Times, "You’re Over 75, and You’re Healthy. Why Are You Taking a Statin?," 5 Jan. 2018
For the 745 who had previously used proton pump inhibitors, the risk declined to 16.1 percent.

— bradley j. fikes, sandiegouniontribune.com, "Stomach acid blockers promote liver disease, study finds," 10 Oct. 2017
The mice were either given a proton pump inhibitor or genetically engineered to lack acid production.

— bradley j. fikes, sandiegouniontribune.com, "Stomach acid blockers promote liver disease, study finds," 10 Oct. 2017
Still, the problem is often treated with GERD drugs known as proton pump inhibitors (PPIs).

— amy norton, chicagotribune.com, "Acid reflux? Try going vegetarian," 12 Sep. 2017
Americans spend nearly $13 billion a year on both prescription and over-the-counter versions of proton pump inhibitors (PPI), the most popular anti-reflux medications.

— alice park, Time, "Acid Reflux May Respond Better To Diet Than Drugs," 7 Sep. 2017
Currently there is increasing concern about drugs called PPIs (proton pump inhibitors) having serious side effects with long-term use.

— Alaska Dispatch News, "Readers write: Letters to the editor, July 23, 2017," 23 July 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'proton pump inhibitor.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of proton pump inhibitor

1983

Medical Dictionary

proton pump inhibitor

noun

medical Definition of proton pump inhibitor

: any of a group of drugs (such as omeprazole and rabeprazole) that inhibit the activity of proton pumps and are used to inhibit gastric acid secretion in the treatment of ulcers and gastroesophageal reflux disease —abbreviation PPI