proton pump inhibitor


: any of a group of drugs that inhibit the activity of pumps transporting hydrogen ions across cell membranes and are used to inhibit gastric acid secretion

Examples of proton pump inhibitor in a Sentence

Recent Examples on the Web Omeprazole is a proton pump inhibitor, or PPI, which blocks the enzymes in the stomach that produce acid. Sean O'Neal, Men's Health, 27 Feb. 2023 Calcium carbonate is not well-absorbed by people taking proton pump inhibitor medicines like omeprazole (Prilosec). Dr. Keith Roach, oregonlive, 2 Dec. 2022 Current clinical practice guidelines recommend the administration of a standard dose of proton pump inhibitor (PPI) for eight weeks as an initial GERD treatment. Joshua Cohen, Forbes, 1 June 2022 Alternative histamine blockers like famotidine (Pepcid) and cimetidine (Tagamet) have so far not been found to contain NDMA, Dr. Smith said, and neither has Prilosec nor other proton pump inhibitors. Christina Caron, New York Times, 18 Apr. 2020 These include popular drugs called proton pump inhibitors (PPIs). Serena Gordon,, 5 Aug. 2019 These include proton pump inhibitors to improve heartburn symptoms, steroids, NSAIDs, and blood pressure medications. Lambeth Hochwald,, 21 June 2019 Sufferers of frequent, recurring heartburn (several times a week) should consider that Zegerid OTC is in the proton pump inhibitor (PPI) class; Pepsid and Zantac, on the other hand, are H2 antagonists. Barbara Brody, Woman's Day, 2 Apr. 2010 The types of medications include hormonal birth control medications, blood pressure and heart medications, proton pump inhibitors, antacids and painkillers. Brett Molina, USA TODAY, 13 June 2018 See More

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'proton pump inhibitor.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

1983, in the meaning defined above

Time Traveler
The first known use of proton pump inhibitor was in 1983

Dictionary Entries Near proton pump inhibitor

Cite this Entry

“Proton pump inhibitor.” Dictionary, Merriam-Webster, Accessed 21 Feb. 2024.

Medical Definition

proton pump inhibitor

: any of a group of drugs (such as omeprazole and rabeprazole) that inhibit the activity of proton pumps and are used to inhibit gastric acid secretion in the treatment of ulcers and gastroesophageal reflux disease
abbreviation PPI

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