omep·​ra·​zole ō-ˈme-prə-ˌzōl How to pronounce omeprazole (audio)
-ˌzȯl How to pronounce omeprazole (audio)
: a benzimidazole derivative C17H19N3O3S that inhibits gastric acid secretion

Examples of omeprazole in a Sentence

Recent Examples on the Web Common brand names include Nexium (esomeprazole), Prilosec (omeprazole), and Protonix (pantoprazole).1 Of note: PPIs do not work for everyone. Karen Pallarito, Health, 6 July 2023 The third group took a combination of curcumin and omeprazole. Kristen Fischer, Health, 24 Sep. 2023 Participants in another group took 20 mg of omeprazole once a day. Kristen Fischer, Health, 24 Sep. 2023 One group got two large capsules of curcumin, a naturally active component to turmeric and a dummy capsule, another got a small omeprazole capsule and two summy capsules four times a day, and the last group got omeprazole and turmeric capsules. Sara Kiley Watson, Popular Science, 13 Sep. 2023 These are powerful acid-suppressing drugs such as esomeprazole (Nexium), lansoprazole (Prevacid) and omeprazole (Prilosec). Joe Graedon and Teresa Graedon, oregonlive, 4 Sep. 2023 Autoimmune gastric atrophy, a bacterial infection (like H. pylori), bariatric surgery, and medicines that reduce stomach acid (like omeprazole) all reduce iron absorption. Dr. Keith Roach, oregonlive, 12 Apr. 2023 Likewise, medications like famotidine (with brand names like Pepcid) and omeprazole (with brand names like Prilosec) can reduce stomach acid secretion. Matt Benoit, Discover Magazine, 18 Feb. 2023 Calcium carbonate is not well-absorbed by people taking proton pump inhibitor medicines like omeprazole (Prilosec). Dr. Keith Roach, oregonlive, 2 Dec. 2022

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'omeprazole.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


International Scientific Vocabulary omepr- (of unknown origin) + benzimidazole

First Known Use

1984, in the meaning defined above

Time Traveler
The first known use of omeprazole was in 1984

Dictionary Entries Near omeprazole

Cite this Entry

“Omeprazole.” Dictionary, Merriam-Webster, Accessed 21 Jul. 2024.

Medical Definition


omep·​ra·​zole ō-ˈmep-rə-ˌzōl How to pronounce omeprazole (audio) -ˈmē-prə- How to pronounce omeprazole (audio)
: a drug C17H19N3O3S that inhibits gastric acid secretion and is taken orally in the short-term treatment of duodenal and gastric ulcers, gastroesophageal reflux disease, erosive esophagitis, and disorders (such as Zollinger-Ellison syndrome) involving gastric acid hypersecretion

Note: Omeprazole is a benzimidazole derivative that acts by inhibiting the activity of proton pumps in the stomach. It is marketed under the trademark Prilosec.

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