omep·​ra·​zole ō-ˈme-prə-ˌzōl How to pronounce omeprazole (audio)
-ˌzȯl How to pronounce omeprazole (audio)
: a benzimidazole derivative C17H19N3O3S that inhibits gastric acid secretion

Example Sentences

Recent Examples on the Web Autoimmune gastric atrophy, a bacterial infection (like H. pylori), bariatric surgery, and medicines that reduce stomach acid (like omeprazole) all reduce iron absorption. Dr. Keith Roach, oregonlive, 12 Apr. 2023 Likewise, medications like famotidine (with brand names like Pepcid) and omeprazole (with brand names like Prilosec) can reduce stomach acid secretion. Matt Benoit, Discover Magazine, 18 Feb. 2023 Calcium carbonate is not well-absorbed by people taking proton pump inhibitor medicines like omeprazole (Prilosec). Dr. Keith Roach, oregonlive, 2 Dec. 2022 If Perrigo had bought omeprazole from a manufacturer and then sold the pills to customers in the United States, its profits would have resided in America. Jesse Drucker, New York Times, 7 July 2022 Many people who have been on omeprazole and similar powerful anti-ulcer drugs for years or decades do just fine if they are slowly tapered off the drug. Dr. Keith Roach, oregonlive, 13 July 2022 No medicine is completely safe, but omeprazole (Prilosec) has been safely used for decades by many people. Dr. Keith Roach, oregonlive, 13 July 2022 Perrigo set up a subsidiary in Israel, with no employees and no offices, to buy the omeprazole. Jesse Drucker, New York Times, 7 July 2022 For myself, even omeprazole is less than $5 - and so much less than OTC versions. Jason Duaine Hahn,, 23 June 2022 See More

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'omeprazole.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


International Scientific Vocabulary omepr- (of unknown origin) + benzimidazole

First Known Use

1984, in the meaning defined above

Time Traveler
The first known use of omeprazole was in 1984

Dictionary Entries Near omeprazole

Cite this Entry

“Omeprazole.” Dictionary, Merriam-Webster, Accessed 10 Jun. 2023.

Medical Definition


omep·​ra·​zole ō-ˈmep-rə-ˌzōl How to pronounce omeprazole (audio) -ˈmē-prə- How to pronounce omeprazole (audio)
: a drug C17H19N3O3S that inhibits gastric acid secretion and is taken orally in the short-term treatment of duodenal and gastric ulcers, gastroesophageal reflux disease, erosive esophagitis, and disorders (such as Zollinger-Ellison syndrome) involving gastric acid hypersecretion

Note: Omeprazole is a benzimidazole derivative that acts by inhibiting the activity of proton pumps in the stomach. It is marketed under the trademark Prilosec.

Last Updated: - Updated example sentences
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