pregnenolone
noun
preg·nen·o·lone
preg-ˈne-nə-ˌlōn 
: an unsaturated hydroxy steroid ketone C21H32O2 that is formed by the oxidation of steroids (such as cholesterol) and yields progesterone on dehydrogenation
Examples of pregnenolone in a Sentence
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There is currently no research on the benefits of pregnenolone for ED.18
Tribulus Terrestris
Tribulus terrestris is an herbal plant used in Traditional Chinese Medicine and Ayurvedic medicine.
—
Jessica Swirble, Verywell Health, 4 Apr. 2025
First, there’s a rise in pregnenolone and progesterone.
—Joshua Hawkins, BGR, 19 May 2022
The authors were able to correct their rats’ behavioural and neurological abnormalities by dosing them with pregnenolone, a drug currently undergoing tests for the treatment of cannabis addiction, schizophrenia, autism and bipolar disorder.
—The Economist, 19 Oct. 2019
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Jessica Swirble, Verywell Health, 4 Apr. 2025
First, there’s a rise in pregnenolone and progesterone.
—Joshua Hawkins, BGR, 19 May 2022
The authors were able to correct their rats’ behavioural and neurological abnormalities by dosing them with pregnenolone, a drug currently undergoing tests for the treatment of cannabis addiction, schizophrenia, autism and bipolar disorder.
—The Economist, 19 Oct. 2019
Cite this Entry
“Pregnenolone.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/pregnenolone. Accessed 5 Jul. 2025.
Copy CitationMedical Definition
pregnenolone
noun
preg·nen·o·lone
preg-ˈnen-ᵊl-ˌōn
: an unsaturated hydroxy steroid ketone C21H32O2 that is formed by the oxidation of steroids (as cholesterol) and yields progesterone on dehydrogenation
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