plaque

noun

ˈplak 

1

a

: an ornamental brooch

especially : the badge of an honorary order

b

: a flat thin piece (as of metal) used for decoration

c

: a commemorative or identifying inscribed tablet

2

a

: a localized abnormal patch on a body part or surface

b

: a sticky usually colorless film on teeth that is formed by and harbors bacteria

c

: an atherosclerotic lesion

d

: a histopathologic lesion of brain tissue that is characteristic of Alzheimer's disease and consists of a dense proteinaceous core composed primarily of beta-amyloid that is often surrounded and infiltrated by a cluster of degenerating axons and dendrites

3

: a clear area in a bacterial culture produced by viral destruction of cells

Examples of plaque in a Sentence

A bronze plaque marked the city's oldest building.

They gave him a plaque in honor of his 30 years of service.

Brushing your teeth prevents the buildup of plaque.

The scientists are studying the way the plaques form.

Recent Examples on the Web

While gum disease treatments typically include cleanings and plaque removal, dentists sometimes turn to topical antibiotics when bacteria and calcified deposits are too difficult to remove, the researchers explained. —Deirdre Bardolf, FOXNews.com, 22 Oct. 2025

For men under 65, artery-narrowing plaques causes three-quarters of heart attacks. —Scott Lafee, San Diego Union-Tribune, 21 Oct. 2025

Extra cholesterol could get in the way of that by contributing to the formation of waxy plaques in your arteries, which can slow blood flow to your heart, Srijana Maharjan, MD, the lead author of the study and an internal medicine resident at Allegheny General Hospital, in Pittsburgh, tells SELF. —Erica Sloan, SELF, 17 Oct. 2025

The temple’s foundation deposits also contained a glass plaque confirming it was dedicated to the goddess Isis, the deity Cleopatra identified with during her reign from 51 BCE to 30 BCE. —Kaif Shaikh, Interesting Engineering, 16 Oct. 2025

Word History

Etymology

French, from Middle French, metal sheet, from plaquer to plate, from Middle Dutch placken to piece, patch; akin to Middle Dutch placke piece, Middle High German placke patch

First Known Use

1845, in the meaning defined at sense 1a

Phrases Containing plaque

• anti-plaque

Rhymes for plaque

• ack
• brack
• clack
• crack
• dak
• flack
• flak
• hack
• jack
• knack
• lac
• lack

Kids Definition

plaque

noun

ˈplak 

1

: an ornamental pin

especially : an honorary badge

2

: a flat thin piece (as of metal) used for decoration or inscribed as a memorial or marker

3

: a sticky usually colorless film on teeth that is formed by and contains bacteria

Medical Definition

plaque

noun

variants also placque

ˈplak 

1

a

: a localized abnormal patch on a body part or surface and especially on the skin

psoriatic plaque

b

: a sticky usually colorless film on teeth that is formed by and harbors bacteria

c

: an atherosclerotic lesion

d

: a histopathologic lesion of brain tissue that is characteristic of Alzheimer's disease and consists of a dense proteinaceous core composed primarily of beta-amyloid that is often surrounded and infiltrated by a cluster of degenerating axons and dendrites

called also senile plaque

2

: a visibly distinct and especially a clear or opaque area in a bacterial culture produced by damage to or destruction of cells by a virus