pi·​per·​a·​zine pi-ˈper-ə-ˌzēn How to pronounce piperazine (audio) pī- How to pronounce piperazine (audio)
: a crystalline heterocyclic base C4H10N2 used especially as an anthelmintic

Examples of piperazine in a Sentence

Recent Examples on the Web Children under 2, anyone with a history of an allergic reaction to Zyrtec or hydroxyzine/piperazine derivatives, and those with severe renal impairment shouldn't take Zyrtec, says Dr. Patel. Jessica Migala, Women's Health, 15 Apr. 2023 Drugs that would be prohibited include any synthetic cannabinoids as well as piperazines or synthetic cathinones that are not approved for use by the U.S. Food and Drug Administration. Monique Garcia, chicagotribune.com, 10 May 2018

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'piperazine.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


International Scientific Vocabulary piperidine + azine

First Known Use

1889, in the meaning defined above

Time Traveler
The first known use of piperazine was in 1889

Dictionary Entries Near piperazine

Cite this Entry

“Piperazine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/piperazine. Accessed 19 May. 2024.

Medical Definition


pi·​per·​a·​zine pī-ˈper-ə-ˌzēn How to pronounce piperazine (audio)
: a crystalline heterocyclic base C4H10N2 or C4H10N2·6H2O used especially as an anthelmintic

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