pi·​per·​a·​zine pi-ˈper-ə-ˌzēn How to pronounce piperazine (audio) pī- How to pronounce piperazine (audio)
: a crystalline heterocyclic base C4H10N2 used especially as an anthelmintic

Example Sentences

Recent Examples on the Web Drugs that would be prohibited include any synthetic cannabinoids as well as piperazines or synthetic cathinones that are not approved for use by the U.S. Food and Drug Administration. Monique Garcia, chicagotribune.com, 10 May 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'piperazine.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

Word History


International Scientific Vocabulary piperidine + azine

First Known Use

1889, in the meaning defined above

Time Traveler
The first known use of piperazine was in 1889

Dictionary Entries Near piperazine

Cite this Entry

“Piperazine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/piperazine. Accessed 2 Feb. 2023.

Medical Definition


pi·​per·​a·​zine pī-ˈper-ə-ˌzēn How to pronounce piperazine (audio)
: a crystalline heterocyclic base C4H10N2 or C4H10N2·6H2O used especially as an anthelmintic

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