oxy·​co·​done | \ ˌäk-sē-ˈkō-ˌdōn \

Definition of oxycodone

: a narcotic analgesic C18H21NO4 used especially in the form of its hydrochloride

Examples of oxycodone in a Sentence

Recent Examples on the Web

About 20 percent of drivers killed in crashes in 2016 tested positive for some kind of opioid, including oxycodone, morphine and fentanyl. Mary Wisniewski, chicagotribune.com, "Fatalities linked to 'drugged' driving keep rising: report," 31 May 2018 Half the deaths involved drugs that contained oxycodone, according to medical examiner records. Fred Schulte, Sun-Sentinel.com, "How America got hooked on the deadly drug OxyContin," 18 June 2018 For instance, oxycodone, cocaine, and heroin were responsible for the most overdose deaths in 2011 (involved in 13.5, 12.3, and 11 percent of deaths, respectively). Sarah Jacoby, SELF, "Fentanyl Now Officially Causes the Most Drug Overdose Deaths in the U.S.," 20 Dec. 2018 Alan Arnold Godofsky, 61, was sentenced for improperly prescribing oxycodone at a clinic in Georgetown. Sarah Brookbank, Cincinnati.com, "Anderson Twp. doctor sentenced to 5 years for oxycodone distribution in Ky.," 27 Apr. 2018 According to federal charges following his 2013 arrest, Pamatmat illegally prescribed 200,000 dosages of oxycodone, and 1 million units of hydrocodone. Milwaukee Journal Sentinel, "More than 200 doctors stay on Medicare rolls despite disciplinary actions," 17 May 2018 AmerisourceBergen distributed nearly 70 million doses of hydrocodone and 29 million doses of oxycodone into the state over a five-year period. Michael Collins, USA TODAY, "House panel to question opioid distributors about pill dumping in West Virginia," 7 May 2018 In 2015, Julie Hamp, a Toyota Motor Corp. public relations executive, an American, was arrested on suspicion of importing oxycodone, a narcotic pain killer, into Japan. Yuri Kageyama, The Seattle Times, "As Ghosn heads for Nissan exit, Renault merger hopes fade," 21 Nov. 2018 Berman also had traces of other medications in her system including oxycodone and anti-depressants. Amy Lieu, Fox News, "Wife of ESPN's Chris Berman was intoxicated at time of fatal crash: report," 31 Aug. 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'oxycodone.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

See More

First Known Use of oxycodone

1963, in the meaning defined above

History and Etymology for oxycodone

oxy + codeine + -one

Keep scrolling for more

Learn More about oxycodone

Statistics for oxycodone

Last Updated

11 Feb 2019

Look-up Popularity

Time Traveler for oxycodone

The first known use of oxycodone was in 1963

See more words from the same year

Keep scrolling for more

More Definitions for oxycodone


oxy·​co·​done | \ -ˈkō-ˌdōn \

Medical Definition of oxycodone

: a narcotic analgesic C18H21NO4 used especially in the form of its hydrochloride C18H21NO4·HCl to relieve moderate to severe pain

Note: Oxycodone is marketed under the trademarks OxyContin, Percocet, and Percodan.

Comments on oxycodone

What made you want to look up oxycodone? Please tell us where you read or heard it (including the quote, if possible).


very full or close together

Get Word of the Day daily email!

Test Your Vocabulary

What did you just call me?! A Quiz

  • rows-of-various-emoji
  • If a member of the audience describes your speech as bombastic, does that person mean it is:
Spell It

Can you spell these 10 commonly misspelled words?


Test Your Knowledge - and learn some interesting things along the way.


Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!