: a narcotic analgesic C18H21NO4 used especially in the form of its hydrochloride

Examples of oxycodone in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Hospital officials reportedly found an allergy medicine inside the patient's prescription bottle, not the prescribed oxycodone, after Wolken exited the bathroom and returned the bottle for the patient to pick up, according to the case document. — Logan Smith, CBS News, 20 Sep. 2026 In the cases of Perry and Miller, prosecutors ultimately secured convictions for the people who supplied Perry with ketamine and Miller with cocaine and oxycodone pills laced with fentanyl. — Richard Winton, Los Angeles Times, 14 Sep. 2026 Hayden Panettiere most likely died after ingesting a single oxycodone pill laced with fentanyl, according to a new report. — Theresa Braine, New York Daily News, 14 Sep. 2026 That year, the head trainer of the Commanders was found to have been illegally distributing oxycodone to players — an unsettling reminder of the NFL's difficult history with painkillers. — ABC News, 28 Aug. 2026 See All Example Sentences for oxycodone

Word History

Etymology

oxy + codeine + -one

First Known Use

1963, in the meaning defined above

Time Traveler
The first known use of oxycodone was in 1963

Browse Nearby Words

Cite this Entry

“Oxycodone.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/oxycodone. Accessed 28 Sep. 2026.

Medical Definition

oxycodone

noun
: a narcotic analgesic C18H21NO4 used especially in the form of its hydrochloride C18H21NO4·HCl to relieve moderate to severe pain

Note: Oxycodone is marketed under the trademarks OxyContin, Percocet, and Percodan.

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

More from Merriam-Webster