: a narcotic analgesic C18H21NO4 used especially in the form of its hydrochloride

Examples of oxycodone in a Sentence

Recent Examples on the Web
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Officers also found more than 460 fentanyl pills, $10,020 in cash and other drugs, including oxycodone and methamphetamine pills, inside and near the vehicle. CBS News, 11 Aug. 2026 Authorities said fentanyl can be sold as pills, with some online dealers claiming the pills are Xanax, Percocet or oxycodone. Rosalio Ahumada, Sacbee.com, 6 Aug. 2026 Perez’s blood tested positive for alcohol, methamphetamine and oxycodone. Brittany Wallman, Miami Herald, 31 July 2026 Chase's mother also spoke out in an interview with the Daily Mail, sharing that her daughter was prescribed oxycodone and other painkillers after a motorcycle accident in 2016, leading to substance abuse issues. Brendan Morrow, USA Today, 29 June 2026 See All Example Sentences for oxycodone

Word History

Etymology

oxy + codeine + -one

First Known Use

1963, in the meaning defined above

Time Traveler
The first known use of oxycodone was in 1963

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Cite this Entry

“Oxycodone.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/oxycodone. Accessed 19 Aug. 2026.

Medical Definition

oxycodone

noun
: a narcotic analgesic C18H21NO4 used especially in the form of its hydrochloride C18H21NO4·HCl to relieve moderate to severe pain

Note: Oxycodone is marketed under the trademarks OxyContin, Percocet, and Percodan.

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