oxy·​co·​done ˌäk-sē-ˈkō-ˌdōn How to pronounce oxycodone (audio)
: a narcotic analgesic C18H21NO4 used especially in the form of its hydrochloride

Example Sentences

Recent Examples on the Web Two men met at a Colorado park in July 2021 for what the buyer thought was a handoff of prescription oxycodone pills, according to court documents. Kyle Melnick, Washington Post, 9 Jan. 2023 An East Hartford pediatrician who served a federal sentence for illegally prescribing oxycodone and failing to pay more than $177,000 in employee withholding taxes to the IRS has voluntarily surrendered his medical license. Kate Farrish, Hartford Courant, 20 Dec. 2022 Prosecutors also pointed to a pharmacy that AmerisourceBergen allegedly knew was its largest purchaser of oxycodone 30mg tablets in all of Colorado. Aaron Katersky, ABC News, 29 Dec. 2022 Authorities learned the pill had been laced with fentanyl, a synthetic opiate over 100 times more potent than oxycodone. Dallas News, 11 Oct. 2022 Deaths attributed to a drug class that includes prescription opioids such as oxycodone pills, once the major factor in the crisis, plateaued in recent years, due in part to tighter regulations on prescriptions. Max Rust And Jon Kamp, WSJ, 14 Dec. 2022 Ben Campofreda turned from prescribed oxycodone to heroin and then fentanyl to treat chronic back pain. Fifth & Mission Podcast, San Francisco Chronicle, 9 Dec. 2022 Investigators were able to determine that Nathans was selling counterfeit versions of Roxicodone pills, one of the brand names under which oxycodone is distributed. Henri Hollis, ajc, 23 Nov. 2022 In the Portland metro area, fentanyl typically has been found pressed into counterfeit prescription pills resembling M30 oxycodone tablets. oregonlive, 17 Nov. 2022 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'oxycodone.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

Word History


oxy + codeine + -one

First Known Use

1963, in the meaning defined above

Time Traveler
The first known use of oxycodone was in 1963

Dictionary Entries Near oxycodone

Cite this Entry

“Oxycodone.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/oxycodone. Accessed 28 Jan. 2023.

Medical Definition


oxy·​co·​done -ˈkō-ˌdōn How to pronounce oxycodone (audio)
: a narcotic analgesic C18H21NO4 used especially in the form of its hydrochloride C18H21NO4·HCl to relieve moderate to severe pain

Note: Oxycodone is marketed under the trademarks OxyContin, Percocet, and Percodan.

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

Fashionable Words

  • dog-sunglasses-scarf
  • Which of these items is named for a deadly weapon?
Name That Thing

You know what it looks like… but what is it called?

Solve today's spelling word game by finding as many words as you can with using just 7 letters. Longer words score more points.

Can you make 12 words with 7 letters?