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oxycodone

noun

oxy·​co·​done ˌäk-sē-ˈkō-ˌdōn How to pronounce oxycodone (audio)
: a narcotic analgesic C18H21NO4 used especially in the form of its hydrochloride

Examples of oxycodone in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
These panels can reliably identify heroin, oxycodone, and fentanyl, but fail to catch nitazenes, brorphine, or other new synthetic analogs. Dr. Shravani Durbhakula, Time, 19 Nov. 2025 This includes heroin, cocaine, opioids like fentanyl and oxycodone, methamphetamine, suboxone and synthetic marijuana. Miami Herald, 7 Nov. 2025 Attorneys for the Angels deny that team officials were aware of Kay’s drug issues or ties to Skaggs, and blame Skaggs’ death on the pitcher combining the pill Kay gave him containing fentanyl with oxycodone and alcohol. Sean Emery, Oc Register, 6 Nov. 2025 Authorities claim that Robertson was working at a rehabilitation center and was responsible for treating multiple patients with oxycodone. Liam Quinn, PEOPLE, 5 Nov. 2025 See All Example Sentences for oxycodone

Word History

Etymology

oxy + codeine + -one

First Known Use

1963, in the meaning defined above

Time Traveler
The first known use of oxycodone was in 1963

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Cite this Entry

“Oxycodone.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/oxycodone. Accessed 29 Nov. 2025.

Medical Definition

oxycodone

noun
oxy·​co·​done -ˈkō-ˌdōn How to pronounce oxycodone (audio)
: a narcotic analgesic C18H21NO4 used especially in the form of its hydrochloride C18H21NO4·HCl to relieve moderate to severe pain

Note: Oxycodone is marketed under the trademarks OxyContin, Percocet, and Percodan.

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