niacinamide

noun

ni·​a·​cin·​amide ˌnī-ə-ˈsi-nə-ˌmīd 

: a compound C₆H₆N₂O of the vitamin B complex found especially as a constituent of coenzymes and used similarly to niacin

called also nicotinamide

Examples of niacinamide in a Sentence

Recent Examples on the Web

The formula has hyaluronic acid and aloe leaf extract for plumping hydration; marshmallow-root and green tea extracts for antioxidant protection; chamomile and cucumber flower extracts to soothe irritation; and niacinamide to brighten. —Jenny Berg, Vogue, 23 Feb. 2026

That’s a doozy to pack into a single tube, and it’s done so with alpha-hydroxy (AHA) and beta-hydroxy (BHA) acids (the aforementioned chemical exfoliants), the brand’s proprietary TruFirm technology, glycerin, and niacinamide. —Tamim Alnuweiri, InStyle, 22 Feb. 2026

To round things out, many formulas include multitaskers like niacinamide and hyaluronic acid for hydration and brightening, plus gentler exfoliants—think PHA or low-dose AHA/BHA blends, so skin gets the benefits of exfoliation without the irritation. —Christa Joanna Lee, Allure, 15 Feb. 2026

Ingredients like niacinamide, peptide, salicylic acid, lactic acid, and glycerin combine to create a powerful formula that delivers instant results. —Claire West, Parents, 13 Feb. 2026

Word History

First Known Use

1942, in the meaning defined above

Rhymes for niacinamide

• acrylamide
• procainamide
• sulfonamide
• sulphonamide
• acetazolamide
• polyacrylamide
• amide
• nicotinamide
• sulfanilamide

Kids Definition

niacinamide

noun

ni·​a·​cin·​amide ˌnī-ə-ˈsin-ə-ˌmīd 

: a compound of the vitamin B complex that is used like niacin

Medical Definition

niacinamide

noun

ni·​a·​cin·​amide ˌnī-ə-ˈsin-ə-ˌmīd 

: a bitter crystalline basic amide C₆H₆N₂O that is a member of the vitamin B complex and is formed from and converted to niacin in the living organism, that occurs naturally usually as a constituent of coenzymes, and that is used similarly to niacin

called also nicotinamide