niacinamide

noun

ni·​a·​cin·​amide ˌnī-ə-ˈsi-nə-ˌmīd 

: a compound C₆H₆N₂O of the vitamin B complex found especially as a constituent of coenzymes and used similarly to niacin

called also nicotinamide

Examples of niacinamide in a Sentence

Recent Examples on the Web

Pracaxi oil, andiroba oil, niacinamide, allantoin, hyaluronic acid, and an Amazonian tree extract give this antioxidant, reparative, anti-inflammatory, collagen-producing, wrinkle-filling, and elasticity-improving benefits. —Tamim Alnuweiri, InStyle, 7 Jan. 2026

Beauty of Joseon Revive Eye Serum Retinal and niacinamide are popular ingredients in anti-aging serums due to their ability to even skin tone and firm wrinkles. —Gabriela Izquierdo, Southern Living, 2 Jan. 2026

What sets this formula apart is the inclusion of ascorbyl glucoside and niacinamide, a vitamin C derivative and brightening staple that improves the look of uneven tone and dark spots over time. —Jailynn Taylor, Allure, 1 Jan. 2026

Also worth trying are Murad Superactive Mattifying Oil + Pore Control Moisturizer SPF 50, a high-factor SPF with oil-reducing niacinamide, and Byoma Blemish Acne Control Moisturizer, which uses salicylic acid to prevent new breakouts while providing deep hydration. —Jacqueline Kilikita, Refinery29, 24 Dec. 2025

Word History

First Known Use

1942, in the meaning defined above

Rhymes for niacinamide

• acrylamide
• procainamide
• sulfonamide
• sulphonamide
• acetazolamide
• polyacrylamide
• amide
• nicotinamide
• sulfanilamide

Kids Definition

niacinamide

noun

ni·​a·​cin·​amide ˌnī-ə-ˈsin-ə-ˌmīd 

: a compound of the vitamin B complex that is used like niacin

Medical Definition

niacinamide

noun

ni·​a·​cin·​amide ˌnī-ə-ˈsin-ə-ˌmīd 

: a bitter crystalline basic amide C₆H₆N₂O that is a member of the vitamin B complex and is formed from and converted to niacin in the living organism, that occurs naturally usually as a constituent of coenzymes, and that is used similarly to niacin

called also nicotinamide