neurodegenerative

adjective

neu·​ro·​de·​gen·​er·​a·​tive ˌnu̇r-ō-di-ˈje-nə-rə-tiv 

-ˈjen-rə-;

-ˈje-nə-ˌrā-;

-dē-, 

ˌnyu̇r-

: relating to or marked by degeneration of nervous tissue

Examples of neurodegenerative in a Sentence

Recent Examples on the Web

Eric Dane, who revealed in April that he'd been diagnosed with ALS, portrayed a firefighter living with the neurodegenerative condition in a recent episode of the NBC drama Brilliant Minds. —Ryan Coleman, Entertainment Weekly, 12 Dec. 2025

Alzheimer’s Disease Adding more cinnamon to your diet may help protect cognitive function, potentially warding off neurodegenerative conditions such as Alzheimer’s disease. —Sarah Bradley, Health, 11 Dec. 2025

Gayheart previously opened up about what co-parenting looks like as Dane battles the progressive neurodegenerative disease. —Stephanie Giang-Paunon, FOXNews.com, 6 Dec. 2025

Eric Dane, who portrays Nate’s father Cal, will also come back amid his recent diagnosis with neurodegenerative disease ALS. —Jami Ganz, Mercury News, 4 Dec. 2025

Word History

First Known Use

1907, in the meaning defined above

Rhymes for neurodegenerative

• degenerative
• regenerative
• generative

Medical Definition

neurodegenerative

adjective

neu·​ro·​de·​gen·​er·​a·​tive -di-ˈjen-ə-ˌrāt-iv, -di-ˈjen-(ə-)rət- 

: relating to or characterized by degeneration of nervous tissue

neurodegeneration

-di-ˌjen-ə-ˈrā-shən, -ˌdē- 

noun