neurodegenerative

adjective

neu·​ro·​de·​gen·​er·​a·​tive ˌnu̇r-ō-di-ˈje-nə-rə-tiv 

-ˈjen-rə-;

-ˈje-nə-ˌrā-;

-dē-,

ˌnyu̇r-

: relating to or marked by degeneration of nervous tissue

Examples of neurodegenerative in a Sentence

Recent Examples on the Web

Its use has since expanded to treat various types of cancer, and researchers are currently exploring its potential to treat diabetes, neurodegenerative diseases and even aging. —Ted Powers, The Conversation, 29 Sep. 2025

Huntington’s disease is a fatal neurodegenerative disease caused by a single genetic mutation, UCL said. —Jenna Prestininzi, Freep.com, 25 Sep. 2025

UniQure — The biotech firm's stock soared nearly 9% after a clinical trial found the company's experimental gene therapy for Huntington's slowed the progress of the neurodegenerative disease. —Michelle Fox, CNBC, 25 Sep. 2025

Doug McConnell, a 67-year-old Chicago-area native who lost both his father and sister to the neurodegenerative disease, founded the organization in 2011. —Melina Khan, USA Today, 22 Sep. 2025

Word History

First Known Use

1907, in the meaning defined above

Rhymes for neurodegenerative

• degenerative
• regenerative
• generative

Medical Definition

neurodegenerative

adjective

neu·​ro·​de·​gen·​er·​a·​tive -di-ˈjen-ə-ˌrāt-iv, -di-ˈjen-(ə-)rət- 

: relating to or characterized by degeneration of nervous tissue

neurodegeneration

-di-ˌjen-ə-ˈrā-shən, -ˌdē- 

noun