neurodegenerative

adjective

neu·​ro·​de·​gen·​er·​a·​tive ˌnu̇r-ō-di-ˈje-nə-rə-tiv 

-ˈjen-rə-;

-ˈje-nə-ˌrā-;

-dē-, 

ˌnyu̇r-

: relating to or marked by degeneration of nervous tissue

Examples of neurodegenerative in a Sentence

Recent Examples on the Web

The progressive neurodegenerative disease affects nerve cells in the brain and spinal cord, according to the national nonprofit ALS Association. —Raechal Shewfelt, Entertainment Weekly, 8 Dec. 2025

Gayheart previously opened up about what co-parenting looks like as Dane battles the progressive neurodegenerative disease. —Stephanie Giang-Paunon, FOXNews.com, 6 Dec. 2025

These particles can damage cells and lead to chronic diseases over time, such as cardiovascular disease, neurodegenerative diseases, and cancer. —Laura Schober, Health, 4 Dec. 2025

Eric Dane, who portrays Nate’s father Cal, will also come back amid his recent diagnosis with neurodegenerative disease ALS. —Jami Ganz, Mercury News, 4 Dec. 2025

Word History

First Known Use

1907, in the meaning defined above

Rhymes for neurodegenerative

• degenerative
• regenerative
• generative

Medical Definition

neurodegenerative

adjective

neu·​ro·​de·​gen·​er·​a·​tive -di-ˈjen-ə-ˌrāt-iv, -di-ˈjen-(ə-)rət- 

: relating to or characterized by degeneration of nervous tissue

neurodegeneration

-di-ˌjen-ə-ˈrā-shən, -ˌdē- 

noun