neurodegenerative

adjective

neu·​ro·​de·​gen·​er·​a·​tive ˌnu̇r-ō-di-ˈje-nə-rə-tiv 

-ˈjen-rə-;

-ˈje-nə-ˌrā-;

-dē-, 

ˌnyu̇r-

: relating to or marked by degeneration of nervous tissue

Examples of neurodegenerative in a Sentence

Recent Examples on the Web

The disruption of this process as we age is thought to contribute to the build-up of malformed proteins and the development of neurodegenerative conditions like Alzheimer’s. —Amanda Erickson, STAT, 7 Apr. 2026

Newer ones such as semaglutide and tirzepatide, broadly known as GLP-1s, have exploded in popularity for weight loss and have shown promise for treating other conditions, such as addictions and neurodegenerative and liver diseases. —Anjeanette Damon, ProPublica, 3 Apr. 2026

Parkinson’s disease, which is a progressive brain disorder, is the fastest-growing neurodegenerative disease in the world. —Patrick Connolly, The Orlando Sentinel, 2 Apr. 2026

For the first time, researchers have developed a new method to transform common plastic into a medication used to treat neurodegenerative Parkinson’s disease. —Mrigakshi Dixit, Interesting Engineering, 16 Mar. 2026

Word History

First Known Use

1907, in the meaning defined above

Phrases Containing neurodegenerative

• neurodegenerative disease
• neurodegenerative disorder

Rhymes for neurodegenerative

• degenerative
• regenerative
• generative

Medical Definition

neurodegenerative

adjective

neu·​ro·​de·​gen·​er·​a·​tive -di-ˈjen-ə-ˌrāt-iv, -di-ˈjen-(ə-)rət- 

: relating to or characterized by degeneration of nervous tissue

neurodegeneration

-di-ˌjen-ə-ˈrā-shən, -ˌdē- 

noun