neu·​ro·​ac·​tive ˌnu̇r-ō-ˈak-tiv How to pronounce neuroactive (audio)
: stimulating neural tissue

Example Sentences

Recent Examples on the Web On the whole, Alpert is encouraged by the many new options on the horizon for treating depression, including magnetic stimulation, neuroactive steroids, ketamine and psychedelic medicines like psilocybin and MDMA. Brianna Randall, Discover Magazine, 7 Apr. 2022 Allopregnanolone is a neuroactive steroid, structurally similar to progesterone, that acts on GABA receptors and is believed to improve symptoms of depression and anxiety by amplifying GABAergic signaling throughout the brain. Husseini Manji, Scientific American, 14 Sep. 2021 To remedy the situation in the meantime, the group came up with a definition for neonatal abstinence syndrome: any baby who is prenatally exposed to any neuroactive substance and exhibits symptoms is diagnosed with NAS. Naseem S. Miller,, 17 Oct. 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'neuroactive.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

Word History

First Known Use

1961, in the meaning defined above

Time Traveler
The first known use of neuroactive was in 1961

Dictionary Entries Near neuroactive

Cite this Entry

“Neuroactive.” Dictionary, Merriam-Webster, Accessed 4 Feb. 2023.

Medical Definition


neu·​ro·​ac·​tive ˌn(y)u̇r-ō-ˈak-tiv How to pronounce neuroactive (audio)
: stimulating neural tissue
injected a neuroactive substance into the blood

More from Merriam-Webster on neuroactive

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