mul·​ti·​sys·​tem | \ ˈməl-tē-ˌsi-stəm How to pronounce multisystem (audio) , -ˌtī- \

Definition of multisystem

: relating to, involving, or consisting of two or more systems … the proliferation of PCs and workstations on desktops, benchtops, and factory floors, has made multisystem communications a way of organizational life.— Ralph Emmett Carlyle specifically : involving or affecting more than one system of bodily organs … a multisystem disorder that most commonly involves the lung and skin but can also present with ear, nose, and throat (ENT) involvement as well as involvement of the cardiovascular, renal, gastrointestinal, and central nervous systems. — Sruthi Renati B. S. et al. … patients often have multisystem injuries that complicate aortic repair. — David G. Neschis

First Known Use of multisystem

1950, in the meaning defined above

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The first known use of multisystem was in 1950

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Cite this Entry

“Multisystem.” Dictionary, Merriam-Webster, Accessed 9 Aug. 2022.

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More Definitions for multisystem


mul·​ti·​sys·​tem | \ -ˌsis-təm How to pronounce multisystem (audio) \
variants: also multi-system or multisystemic \ -​sis-​ˈtem-​ik How to pronounce multisystem (audio) \

Medical Definition of multisystem

: relating to, involving, or affecting more than one bodily system systemic lupus erythematosus is a multisystem disease died of multisystem organ failure


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