mo·​sa·​i·​cism mō-ˈzā-ə-ˌsi-zəm How to pronounce mosaicism (audio)
: the condition of possessing cells of two or more different genetic constitutions

Examples of mosaicism in a Sentence

Recent Examples on the Web Those who showed any other chromosomes, or a mosaicism of chromosomes, were at times advised to fake a last-minute injury and to quietly retire from sports. S. C. Cornell, The New Yorker, 2 Dec. 2023 Less common types of Down syndrome are translocation and mosaicism. Ashlyn Messier, Fox News, 8 Oct. 2023 According to the team on this study, this mixture shows the impact of evolutionary mosaicism–different rates of evolutionary change in body structures and function– in early bird evolution. Laura Baisas, Popular Science, 6 Sep. 2023 When the protocol is safe—when the problems of unintended mutations and mosaicism are solved in the lab—the urgency of exploiting the new technology to save lives seems likely to push any remaining reservations aside. Dana Goodyear, The New Yorker, 2 Sep. 2023 This mix of cell lines is called mosaicism. Laura Hercher, Scientific American, 1 June 2022 These include, for example, mosaicism, where genome editing results in some cells getting different edits to others. WIRED, 17 Mar. 2023 This kind of mosaicism is rare, affecting about 1 in 15,000 people. Claire Ainsworth, Scientific American, 22 Oct. 2018 Sultan also told the woman the test results were likely due to a rare condition called mosaicism, where a person can have two sets of DNA in their body, court records state. Washington Post, 1 Dec. 2021 See More

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'mosaicism.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

1920, in the meaning defined above

Time Traveler
The first known use of mosaicism was in 1920

Dictionary Entries Near mosaicism

Cite this Entry

“Mosaicism.” Dictionary, Merriam-Webster, Accessed 21 Feb. 2024.

Medical Definition


mo·​sa·​i·​cism mō-ˈzā-ə-ˌsiz-əm How to pronounce mosaicism (audio)
: the condition of possessing cells of two or more different genetic constitutions

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