mo·​sa·​i·​cism | \ mō-ˈzā-ə-ˌsi-zəm How to pronounce mosaicism (audio) \

Definition of mosaicism

: the condition of possessing cells of two or more different genetic constitutions

Examples of mosaicism in a Sentence

Recent Examples on the Web There are three types of Down syndrome: translocation, mosaicism and trisomy 21. Cnn Editorial Research, CNN, 28 May 2021 That problem, known as mosaicism, needs to be solved to produce useful animal models. Gary Stix, Scientific American, 15 Nov. 2016 Individual embryos also had cells that were edited in different ways, a concept called mosaicism. Andrew Joseph, STAT, 3 Sep. 2020 Findings made in the past few years reveal that human skin, oesophageal and lung cells show high levels of mosaicism. Kendall Powell, Scientific American, 22 Jan. 2020 But the key, says Martincorena, is that the latest analysis demonstrated that mosaicism is present across a wide array of tissues. Heidi Ledford, Scientific American, 14 June 2019 Previous studies have found high levels of mosaicism in the skin, oesophagus and blood. Heidi Ledford, Scientific American, 14 June 2019 Plus, both babies have a combination of cells with an edit and without an edit, which is called mosaicism. Angela Chen, The Verge, 29 Nov. 2018 But scientists are also finding that mosaicism does not automatically equal disease. New York Times, 21 May 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'mosaicism.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of mosaicism

1920, in the meaning defined above

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The first known use of mosaicism was in 1920

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Statistics for mosaicism

Last Updated

11 Jun 2021

Cite this Entry

“Mosaicism.” Dictionary, Merriam-Webster, Accessed 24 Jul. 2021.

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More Definitions for mosaicism


mo·​sa·​i·​cism | \ mō-ˈzā-ə-ˌsiz-əm How to pronounce mosaicism (audio) \

Medical Definition of mosaicism

: the condition of possessing cells of two or more different genetic constitutions

More from Merriam-Webster on mosaicism Encyclopedia article about mosaicism


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