mosaicism

noun
mo·​sa·​i·​cism | \ mō-ˈzā-ə-ˌsi-zəm How to pronounce mosaicism (audio) \

Definition of mosaicism

: the condition of possessing cells of two or more different genetic constitutions

Examples of mosaicism in a Sentence

Recent Examples on the Web Findings made in the past few years reveal that human skin, oesophageal and lung cells show high levels of mosaicism. Kendall Powell, Scientific American, "Survival of the Fittest Cells," 22 Jan. 2020 But the key, says Martincorena, is that the latest analysis demonstrated that mosaicism is present across a wide array of tissues. Heidi Ledford, Scientific American, "The Human Body Is a Mosaic of Different Genomes," 14 June 2019 Previous studies have found high levels of mosaicism in the skin, oesophagus and blood. Heidi Ledford, Scientific American, "The Human Body Is a Mosaic of Different Genomes," 14 June 2019 Plus, both babies have a combination of cells with an edit and without an edit, which is called mosaicism. Angela Chen, The Verge, "Flawed DNA editing of alleged ‘designer babies’ may have put their health at risk," 29 Nov. 2018 But scientists are also finding that mosaicism does not automatically equal disease. New York Times, "Every Cell in Your Body Has the Same DNA. Except It Doesn’t.," 21 May 2018 Most of the excess was found in the hippocampus, a region of the brain involved in memory, but not in other regions of the brain, nor in a completely different organ like the heart, suggesting a very specific impact on brain mosaicism. Robert Martone, Scientific American, "Early Life Experience: It’s in Your DNA," 10 July 2018 Some skin diseases proved to be caused by mosaicism, too. New York Times, "Every Cell in Your Body Has the Same DNA. Except It Doesn’t.," 21 May 2018 An article on Tuesday about the genetic condition mosaicism misstated the year in which Theodor Boveri died. New York Times, "Corrections: May 23, 2018," 22 May 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'mosaicism.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of mosaicism

1920, in the meaning defined above

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The first known use of mosaicism was in 1920

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Cite this Entry

“Mosaicism.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/mosaicism. Accessed 8 Aug. 2020.

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More Definitions for mosaicism

mosaicism

noun
mo·​sa·​i·​cism | \ mō-ˈzā-ə-ˌsiz-əm How to pronounce mosaicism (audio) \

Medical Definition of mosaicism

: the condition of possessing cells of two or more different genetic constitutions

More from Merriam-Webster on mosaicism

Britannica.com: Encyclopedia article about mosaicism

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