microbiome

noun

mi·​cro·​bi·​ome ˌmī-krō-ˈbī-ˌōm 

1

: a community of microorganisms (such as bacteria, fungi, and viruses) that inhabit a particular environment and especially the collection of microorganisms living in or on the human body

Your body is home to about 100 trillion bacteria and other microbes, collectively known as your microbiome.

—Carl Zimmer

… what's arguably become the hottest area of medicine: microbiome research, an emerging field that's investigating how the bacteria that live in and on our bodies affect our health.

—Sunny Sea Gold

2

: the collective genomes of microorganisms inhabiting a particular environment and especially the human body

They form one community among the many that make up the human microbiome: the full genetic complement of bacteria and other organisms at home on your skin, gums, and teeth, in your genital tract, and especially in your gut.

—Nathan Wolfe

Examples of microbiome in a Sentence

Recent Examples on the Web

And as for the peptide itself, genetic material that codes for its unique amino acid sequence hasn’t been found in the human genome or gut microbiome. —Sara Talpos — Undark, STAT, 1 June 2026

Now the vaginal microbiome has gone mainstream. —Helen Carefoot, Flow Space, 28 May 2026

The formula also packs in microbiome-friendly ferments like Lactobacillus, Lactococcus, Bifida, and Saccharomyces extracts, alongside a nourishing blend of rosemary, peppermint, argan, castor, moringa, rosehip, jojoba, and soybean oils to support both scalp health and softer, silkier strands. —Christa Joanna Lee, Allure, 27 May 2026

The global gut-health category has exploded commercially over the past decade, fuelled by rising awareness of the microbiome’s relationship with immunity, cognition, mood, inflammation and hormonal regulation. —Kate Hardcastle, Forbes.com, 27 May 2026

Word History

Etymology

micro- + biome

First Known Use

1952, in the meaning defined at sense 1

Rhymes for microbiome

• diatom
• intercom
• aplomb
• balaam
• begam
• cocom
• embalm
• islam
• pogrom
• salaam
• sitcom
• balm

Medical Definition

microbiome

noun

mi·​cro·​bi·​ome ˌmī-krō-ˈbī-ˌōm 

1

: a community of microorganisms (such as bacteria, fungi, and viruses) that inhabit a particular environment and especially the collection of microorganisms living in or on the human body

The intestinal microbiome consists of the microorganisms that inhabit the gut.

—Clara Abraham et al., The New England Journal of Medicine

Collectively known as the microbiome, this community may play a role in regulating one's risk of obesity, asthma and allergies.

—Carrie Arnold, Scientific American

The human oral microbiome comprises all microbial species in the oral cavity.

—Naomi P. O'Grady, The Journal of the American Medical Association

2

: the collective genomes of microorganisms inhabiting a particular environment and especially the human body

As part of a new citizen-science initiative called the American Gut project, the lab sequenced my microbiome—that is, the genes not of "me," exactly, but of the several hundred microbial species with whom I share this body.

—Michael Pollan, The New York Times

Together, the genomes of these microbial symbionts (collectively defined as the microbiome) provide traits that humans did not need to evolve on their own.

—Peter J. Turnbaugh et al., Nature