Definition of methotrexate
: a toxic folic acid analog C20H22N8O5 that is used to treat certain cancers, severe psoriasis, and rheumatoid arthritis
Recent Examples of methotrexate from the Web
Doctors treated him for rheumatoid arthritis, but a cocktail of medicines — including methotrexate, a chemotherapy drug given to cancer patients — proved ineffective.
The note was tucked away in a file on methotrexate, a drug that can be used to end a pregnancy within the first seven weeks.
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Origin and Etymology of methotrexate
meth- + -trexate, of unknown origin
First Known Use: 1955See Words from the same year
Medical Definition of methotrexate
: a toxic drug C20H22N8O5 that is an analog of folic acid and is used to treat certain cancers, severe psoriasis, and rheumatoid arthritis—called also amethopterin
Learn More about methotrexate
Britannica.com: Encyclopedia article about methotrexate
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