mega·​dose ˈme-gə-ˌdōs How to pronounce megadose (audio)
: a large dose (as of a vitamin)

Example Sentences

He took megadoses of vitamin C.
Recent Examples on the Web Logging on already provides a daily megadose of paranoia (mass surveillance), epistemic vertigo (deepfakes), and fremdschämen (thirstposting). Meghan O'gieblyn, Wired, 16 Sep. 2020 The play encapsulated so many of the defining football characteristics Bernard brought to the Bengals that year (and years since): elusivity, creativity, electricity, relentlessness and a megadose of fun. Paul Dehner Jr.,, 27 June 2018 Perhaps a megadose of LSD, or a shroom trip, or one more ayahuasca ceremony will finally heal me. Stuart Leach, Washington Post, 25 Mar. 2018 Arkansas’ protocol calls for a 500-miligram megadose of midazolam. Washington Post, 26 Apr. 2017 The network has been turning politics into sport for nearly 20 years: Zucker just gave the model a megadose of steroids. New York Times, 21 Apr. 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'megadose.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

Word History

First Known Use

1971, in the meaning defined above

Time Traveler
The first known use of megadose was in 1971

Dictionary Entries Near megadose

Cite this Entry

“Megadose.” Dictionary, Merriam-Webster, Accessed 21 Mar. 2023.

Kids Definition


mega·​dose -ˌdōs How to pronounce megadose (audio)
: a large dose (as of a vitamin)

Medical Definition


mega·​dose -ˌdōs How to pronounce megadose (audio)
: a large dose (as of a vitamin)
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