major depressive disorder

noun

Definition of major depressive disorder 

: a mood disorder having a clinical course involving one or more episodes of serious psychological depression lasting two or more weeks each with no intervening episodes of mania

Examples of major depressive disorder in a Sentence

Recent Examples on the Web

Marshall said his wife suffered major depressive disorder and anxiety. CBS News, "Alabama Attorney General Steve Marshall recalls final call with wife before her suicide," 29 June 2018 He was admitted to Wentworth in October 2016, with diagnoses of major depressive disorder, cocaine use and lung disease, reports state. Sam Roe, chicagotribune.com, "Inside Chicago's worst nursing home: bug bites, bruises and death," 13 June 2018 Her son, Kurt Skelley, took his own life in 2014 after struggling with major depressive disorder, a form of depression. Hayley Harding, courant.com, "Memorial Lacrosse Game Saturday To Honor Life Of Avon Grad," 14 June 2018 According to the findings, published June 22 in Science, conditions such as schizophrenia, major depressive disorder (MDD) and bipolar disorder share a suite of overlapping genetic variants rather than having distinct genetic signatures. Emily Willingham, Scientific American, "Analysis of a Million-Plus Genomes Points to Blurring Lines Among Brain Disorders," 22 June 2018 Doctors diagnosed him with generalized anxiety disorder, major depressive disorder and disruptive mood dysregulation disorder, according to the documents. Vikki Ortiz, chicagotribune.com, "CPS students denied special education services amid 'cycle of chaos,' parents say," 19 June 2018 Treatment for persistent and major depressive disorder is similar, but some experts view PDD as being harder to tame. Christina Stiehl, SELF, "The Difference Between Depression and Persistent Depressive Disorder, aka Dysthymia," 4 May 2018 If clinical trials are positive, the FDA will allow Sage to seek approval for SAGE-217 to treat major depressive disorder and postpartum depression faster than previously expected. Adam Feuerstein, STAT, "Sage Therapeutics gets ‘go faster’ permission from FDA on oral depression drug," 12 June 2018 The results of the study concluded that neither gender nor economic status seemed to increase the likelihood of major depressive disorders in African-American youths. Michael Harriot, The Root, "Study: Affluent Black Kids Suffer Higher Rates of Depression Because ... You Guessed It: Racism," 15 May 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'major depressive disorder.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

See More

First Known Use of major depressive disorder

1978, in the meaning defined above

Keep scrolling for more

Learn More about major depressive disorder

Share major depressive disorder

Resources for major depressive disorder

Statistics for major depressive disorder

Look-up Popularity

Time Traveler for major depressive disorder

The first known use of major depressive disorder was in 1978

See more words from the same year

Keep scrolling for more

More Definitions for major depressive disorder

major depressive disorder

noun

Medical Definition of major depressive disorder 

: a mood disorder having a clinical course involving one or more episodes of serious psychological depression that last two or more weeks each, do not have intervening episodes of mania or hypomania, and are characterized by a loss of interest or pleasure in almost all activities and by some or all of disturbances of appetite, sleep, or psychomotor functioning, a decrease in energy, difficulties in thinking or making decisions, loss of self-esteem or feelings of guilt, and suicidal thoughts or attempts — compare bipolar disorder

Comments on major depressive disorder

What made you want to look up major depressive disorder? Please tell us where you read or heard it (including the quote, if possible).

WORD OF THE DAY

exaggeratedly or childishly emotional

Get Word of the Day daily email!

Test Your Vocabulary

Words from Greek and Roman Mythology Quiz

  • the-triumph-of-venus-by-alessandro-magnasco
  • Boreal comes from the name of the ancient Greek god of which wind?
True or False

Test your knowledge - and maybe learn something along the way.

TAKE THE QUIZ
Word Winder's CrossWinder

Test Your Knowledge - and learn some interesting things along the way.

TAKE THE QUIZ

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!