major depressive disorder

noun
Updated on: 22 Apr 2018

Definition of major depressive disorder

: a mood disorder having a clinical course involving one or more episodes of serious psychological depression lasting two or more weeks each with no intervening episodes of mania

Recent Examples of major depressive disorder from the Web

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'major depressive disorder.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of major depressive disorder

1978

in the meaning defined above

See Words from the same year
NEW! Time Traveler

Medical Dictionary

major depressive disorder

noun

medical Definition of major depressive disorder

: a mood disorder having a clinical course involving one or more episodes of serious psychological depression that last two or more weeks each, do not have intervening episodes of mania or hypomania, and are characterized by a loss of interest or pleasure in almost all activities and by some or all of disturbances of appetite, sleep, or psychomotor functioning, a decrease in energy, difficulties in thinking or making decisions, loss of self-esteem or feelings of guilt, and suicidal thoughts or attempts — compare bipolar disorder

Seen and Heard

What made you want to look up major depressive disorder? Please tell us where you read or heard it (including the quote, if possible).

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

WORD OF THE DAY

a large number

Get Word of the Day daily email!

Test Your Vocabulary

Odd Habits and Quirks Quiz

  • image1926873504
  • Which of the following best describes an easily irritated person?
How Strong Is Your Vocabulary?

Test your vocabulary with our 10-question quiz!

TAKE THE QUIZ
Word Winder's CrossWinder

Test Your Knowledge - and learn some interesting things along the way.

TAKE THE QUIZ

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!