major depression


Definition of major depression 

2 : an episode of depression characteristic of major depressive disorder

Examples of major depression in a Sentence

Recent Examples on the Web

Researchers compared genetic analyses of 700 human brains from deceased individuals who had one of those three disorders, major depression or alcoholism (columns) with brains of individuals who had none of the conditions. Mark Fischetti, Scientific American, "The Same Genes May Underlie Different Psychiatric Disorders," 12 July 2018 About 10% of people with major depression die of suicide. Liz Szabo, USA TODAY, "Kate Spade’s death ignites concern about rising suicide rate," 7 June 2018 Besides schizophrenia, bipolar disorder and major depression, these include obsessive-compulsive disorder, anorexia nervosa and Tourette’s syndrome. The Economist, "A big collaboration is trying to understand diseases of the psyche," 28 June 2018 Four serious side effects were reported during the course of the study, though three of these events -- suicide ideation, major depression and appendicitis -- were not attributed to MDMA. Susan Scutti, CNN, "MDMA enhances treatment for veterans with PTSD, study finds," 1 May 2018 The benefits also applied only to people who were suffering from major depression, specifically in the short term. New York Times, "Do Antidepressants Work?," 12 Mar. 2018 Bipolar disorder, for example, was more similar to schizophrenia than to major depression even though clinicians may link bipolar disorder and depression, based on their symptoms. Mark Fischetti, Scientific American, "The Same Genes May Underlie Different Psychiatric Disorders," 12 July 2018 In May, Myriad Genetics released the first large-scale test of whether treatment guided by genetics (pharmacogenomics) would improve overall outcomes for patients with major depression. Courtenay Harris Bond,, "Which antidepressant is right for you? This genetic test could help," 11 July 2018 In a study published in Lancet Psychiatry, Dutch researchers followed 1,042 people ages 18 to 88 with diagnoses of major depression. Nicholas Bakalar, New York Times, "Depression in Older People Tends to Be More Severe," 7 June 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'major depression.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of major depression

1979, in the meaning defined at sense 1

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Last Updated

19 Oct 2018

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The first known use of major depression was in 1979

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major depression


Medical Definition of major depression 

: an episode of depression characteristic of major depressive disorder also : major depressive disorder

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