major depression


Definition of major depression

2 : an episode of depression characteristic of major depressive disorder

Examples of major depression in a Sentence

Recent Examples on the Web

Researchers compared genetic analyses of 700 human brains from deceased individuals who had one of those three disorders, major depression or alcoholism (columns) with brains of individuals who had none of the conditions. Mark Fischetti, Scientific American, "The Same Genes May Underlie Different Psychiatric Disorders," 12 July 2018 About 10% of people with major depression die of suicide. Liz Szabo, USA TODAY, "Kate Spade’s death ignites concern about rising suicide rate," 7 June 2018 It’s defined as major depression that follows a seasonal pattern for at least two years, according to the National Institutes for Mental Health. Jamie Ducharme, Time, "Seasonal Depression Doesn't Just Happen in the Winter. Here's What to Know About Summertime Sadness," 5 June 2018 One in 25 Americans has a serious mental illness, such as schizophrenia, bipolar disorder or major depression. Rebecca Lurye,, "Aetna VP Shares Battle With Mental Illness In New Documentary," 1 June 2018 Massive study finds nearly half of US feels alone, young adults most of all More than nine million commercially insured Americans in the index are affected by major depression. Fiza Pirani, ajc, "Major depression diagnoses in US up 33 percent since 2013, study finds," 11 May 2018 Four serious side effects were reported during the course of the study, though three of these events -- suicide ideation, major depression and appendicitis -- were not attributed to MDMA. Susan Scutti, CNN, "MDMA enhances treatment for veterans with PTSD, study finds," 1 May 2018 My psychiatrist told me major depression changes the logic of your brain. Danielle Tcholakian, The Cut, "What It’s Like to Know You’ll Be on Antidepressants for Life," 12 Apr. 2018 As my case illustrates, major depression affects the entire family. Courtenay Harris Bond,, "In despair from major depression, I turned to a last resort: Magnets," 14 Mar. 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'major depression.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of major depression

1979, in the meaning defined at sense 1

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Last Updated

24 Aug 2019

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The first known use of major depression was in 1979

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More Definitions for major depression

major depression


Medical Definition of major depression

: an episode of depression characteristic of major depressive disorder also : major depressive disorder

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one from the Upper Peninsula of Michigan

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