macula

noun

mac·​u·​la ˈma-kyə-lə 

plural maculae ˈma-kyə-ˌlē  -ˌlī  also maculas

1

: spot, blotch

especially : macule

2

a

: an anatomical structure having the form of a spot differentiated from surrounding tissues

b

: a small yellowish area lying slightly lateral to the center of the retina that is made up mostly of cones (see cone entry 1 sense 3a), plays a key role in visual acuity, and has the fovea at its center

called also macula lutea, yellow spot

macular

ˈma-kyə-lər 

adjective

Examples of macula in a Sentence

Recent Examples on the Web

The disease progressively destroys photoreceptors in the macula, the central portion of the retina responsible for recognizing images and resolving fine details. — New Atlas, 5 Aug. 2026

These two antioxidant compounds are best known for their role in eye health, particularly in protecting the macula from oxidative damage. — Anna Giorgi, Verywell Health, 2 July 2026

The condition develops when fluid builds up in the macula — the central portion of the retina at the back of the eye, where vision is sharpest. — Samantha Agate, Charlotte Observer, 1 May 2026

The antioxidants build up in the macula, which is the part of your eye that controls sharp, central vision. — Lindsay Curtis, Health, 12 Nov. 2025

Word History

Etymology

Middle English, borrowed from Latin, "stain, spot, blemish, one of the interstices of a net," of uncertain origin

Note: If macula goes back to *sma-tlā, then *sma- may represent an Indo-European base *smh₁- seen in Greek smáō, smân "to cleanse, wipe clean," smêma "ointment."

First Known Use

15th century, in the meaning defined at sense 1

Phrases Containing macula

• macula lutea

Rhymes for macula

• dracula

Medical Definition

macula

noun

mac·​u·​la ˈmak-yə-lə 

plural maculae -ˌlē  -ˌlī  also maculas

1

: a spot or blotch

especially : macule sense 2

2

: an anatomical structure having the form of a spot differentiated from surrounding tissues: as

a

: macula acustica

b

: a small yellowish area lying slightly lateral to the center of the retina that is made up mostly of cones, plays a key role in visual acuity, and has the fovea at its center

called also macula lutea, yellow spot