macule

noun

mac·ule | \ ˈma-(ˌ)kyü(ə)l

Definition of macule

: a patch of skin that is altered in color but usually not elevated … erythema migrans is defined as a skin lesion that typically begins as a red macule or papule and expands over a period of days to weeks to form a large round lesion, often with partial central clearing.— Carrie D. Tibbles et al.

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The first known use of macule was in 1863

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macule

noun

mac·ule | \ ˈmak-(ˌ)yü(ə)l

Medical Definition of macule

1 : macula sense 2

2 : a patch of skin that is altered in color but usually not elevated Target-like macules with a dusky center are usually pathognomonic for the disorder but may not always be present.— Barry Ladizinski and Kachiu C. Lee, The Journal of the American Medical Association, 19 Mar. 2014 The lesions begin as 1 to 3 mm macules that gradually become confluent, assuming a reticulated lacelike pattern.— Pearl E. Grimes, Scientific American Medicine Bulletin, April 2000