Definition of macule
: a patch of skin that is altered in color but usually not elevated
… erythema migrans is defined as a skin lesion that typically begins as a red macule or papule and expands over a period of days to weeks to form a large round lesion, often with partial central clearing.— Carrie D. Tibbles et al.
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Merriam-Webster unabridged
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Time Traveler for macule
The first known use of macule was in 1863
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