\ˈläkt-ˈin \

Definition of locked-in 

1 : not subject to adjustment : fixed locked-in interest rates

2 : unable or unwilling to shift invested funds because of the tax effect of realizing capital gains

First Known Use of locked-in

1967, in the meaning defined at sense 1

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The first known use of locked-in was in 1967

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\ˈläk-ˈtin \

Medical Definition of locked-in 

: affected with, characterized by, or relating to the locked-in syndrome Locked-in patients have lost the ability to control the body voluntarily, but they retain some ability to control the face. Often they can move only their eyes. Although they are conscious, they are unable to communicate.— David E. Levy, Discover, May 1998 A locked-in diagnosis (the term was first used in 1966 by the American neurologists Jerome Posner and Fred Plum) means that although a person has been abandoned by his or her body, the brain still functions. The most clear evidence for this is usually some residual voluntary eye movement, a deliberate response to “Blink if you hear me.”— Ian Parker, The New Yorker, 20 Jan. 2003

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playful or foolish behavior

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