in·​ves·​ti·​ga·​tion·​al | \ in-ˌve-stə-ˈgā-shnəl How to pronounce investigational (audio) , -shə-nᵊl\

Definition of investigational

1 : of or relating to investigation investigational activities
2 : relating to or being a drug or medical procedure that is not approved for general use but is under investigation in clinical trials regarding its safety and efficacy an investigational new drug

Examples of investigational in a Sentence

Recent Examples on the Web

In denying the ventilator, Health Net classified the device as an experimental or investigational service, the lawsuit states. Ken Alltucker, USA TODAY, "ALS activist who gained notoriety for quizzing Sen. Flake sues insurer," 2 July 2018 The first is a combination investigational antibody and drug that targets a protein called B-cell maturation antigen, or BCMA. Clifton Leaf, Fortune, "GSK’s New CEO Emma Walmsley Has a Strong Start Out of the Gate," 8 June 2018 Congress took a small step in the right direction this May by passing a Right to Try law, which theoretically grants terminal patients the right to access investigational drugs that haven’t shown clinical efficacy. Paul J. Marangos, WSJ, "The Terminally Ill Need More Than the ‘Right to Try’," 13 Aug. 2018 The bill would, in effect, allow dying patients to bypass the Food and Drug Administration and obtain an ‘investigational drug’ with the approval of their doctors, if the drug manufacturer agrees to supply it. Chris Stirewalt, Fox News, "Fox News Power Rankings: Dem divides emerge," 23 May 2018 The two trials were to evaluate the safety and efficacy of a gene therapy for beta thalassemia using LentiGlobin, an investigational therapy by Bluebird Bio. Jacqueline Howard, CNN, "Gene therapy helps patients avoid blood transfusion," 18 Apr. 2018 The paper notes that the FDA already has expanded-access policies, sometimes called compassionate use, to give terminally ill patients without other options access to investigational medical products outside of clinical trials. Jacqueline Howard, CNN, "What you need to know about right-to-try legislation," 22 Mar. 2018 In March, the House passed legislation aimed at giving seriously ill patients increased access to investigational drugs, a bill championed by Vice President Mike Pence. USA TODAY, "Live stream: President Trump signs the "Right to Try Act"," 30 May 2018 Sadly, Senate Minority Leader Chuck Schumer (D-NY) chose to block sick patients from access to investigational drugs. Erin Mershon, STAT, "Right-to-try bill headed for vote puts bigger burden on FDA to protect patients, Gottlieb says," 17 May 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'investigational.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of investigational

1905, in the meaning defined at sense 1

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Last Updated

10 Aug 2019

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The first known use of investigational was in 1905

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