in·ves·ti·ga·tion·al | \in-ˌve-stə-ˈgā-shnəl, -shə-nᵊl\

Definition of investigational 

1 : of or relating to investigation investigational activities

2 : relating to or being a drug or medical procedure that is not approved for general use but is under investigation in clinical trials regarding its safety and efficacy an investigational new drug

Examples of investigational in a Sentence

Recent Examples on the Web

The bill would, in effect, allow dying patients to bypass the Food and Drug Administration and obtain an ‘investigational drug’ with the approval of their doctors, if the drug manufacturer agrees to supply it. Chris Stirewalt, Fox News, "Fox News Power Rankings: Dem divides emerge," 23 May 2018 The two trials were to evaluate the safety and efficacy of a gene therapy for beta thalassemia using LentiGlobin, an investigational therapy by Bluebird Bio. Jacqueline Howard, CNN, "Gene therapy helps patients avoid blood transfusion," 18 Apr. 2018 The paper notes that the FDA already has expanded-access policies, sometimes called compassionate use, to give terminally ill patients without other options access to investigational medical products outside of clinical trials. Jacqueline Howard, CNN, "What you need to know about right-to-try legislation," 22 Mar. 2018 In March, the House passed legislation aimed at giving seriously ill patients increased access to investigational drugs, a bill championed by Vice President Mike Pence. USA TODAY, "Live stream: President Trump signs the "Right to Try Act"," 30 May 2018 Sadly, Senate Minority Leader Chuck Schumer (D-NY) chose to block sick patients from access to investigational drugs. Erin Mershon, STAT, "Right-to-try bill headed for vote puts bigger burden on FDA to protect patients, Gottlieb says," 17 May 2018 Right to try': Pence, 2nd-grader get surprising pushback Indianapolis second-grader Jordan McLinn has been the adorable face of a national push to give seriously ill patients increased access to investigational drugs. Indystar, Indianapolis Star, "Legislative extension, students united by fear and a clash over bunny business," 21 Mar. 2018 With such promising lab results, the team got an emergency investigational new drug approval from the Food and Drug Administration to treat the sick doctor with their pond phage. Beth Mole, Ars Technica, "Virus fished from pond cures man’s deadly antibiotic-resistant infection," 20 Mar. 2018 Patients, under the advice of their doctors, would be able to reach out to a drug manufacturer to request an investigational therapy without having to go through the FDA. Sy Mukherjee, Fortune, "Trump Called for a 'Right to Try' Law During His State of the Union. Here's What That Means," 1 Feb. 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'investigational.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of investigational

1905, in the meaning defined at sense 1

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Last Updated

21 Sep 2018

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The first known use of investigational was in 1905

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exaggeratedly or childishly emotional

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