intoxication

noun

in·​tox·​i·​ca·​tion in-ˌtäk-sə-ˈkā-shən 

1

a

: the condition of having physical or mental control markedly diminished by the effects of alcohol or drugs

drank to the point of intoxication

cocaine intoxication

b

: a strong excitement or elation

The mere knowledge that they are on an island, a little world entirely surrounded by the sea, fills them with an indescribable intoxication …

—Christine Osborne

2

: an abnormal state that is essentially a poisoning

carbon monoxide intoxication

Synonyms of intoxication

• alcoholism
• inebriation
• drunkenness
• inebriety

Examples of intoxication in a Sentence

there's a firm distinction between the moderate consumption of alcoholic beverages and overindulgence to the point of intoxication

the intoxication felt by two people who have just fallen in love

Recent Examples on the Web

She was arrested by the Brownwood Police Department in July of 2025 on charges of public intoxication and resisting arrest, search or transport. —Briauna Brown, CBS News, 12 May 2026

What Tim described didn’t sound like intoxication. —Jonathan Avery, STAT, 11 May 2026

The accident is often caused by negligence, intoxication, or distraction, and in the case of hit-and-runs, the act of leaving the crash scene itself. —Matt Emma, USA Today, 8 May 2026

Ghio also mentioned Marcello Meadows, a 10-month-old who died of fentanyl, xylazine, and cocaine intoxication in June of 2023. —Kaitlin McCallum, Hartford Courant, 30 Apr. 2026

Word History

First Known Use

1624, in the meaning defined at sense 1a

Rhymes for intoxication

• abbreviation
• abomination
• acceleration
• accentuation
• accommodation
• accreditation
• acculturation
• accumulation
• acetylation
• adjudication
• administration
• adulteration

Kids Definition

intoxication

noun

in·​tox·​i·​ca·​tion in-ˌtäk-sə-ˈkā-shən 

1

a

: an unhealthy state that is or is like a poisoning

carbon monoxide intoxication

b

: the condition of being drunk

2

: a strong excitement or elation

the intoxication of success

Medical Definition

intoxication

noun

in·​tox·​i·​ca·​tion in-ˌtäk-sə-ˈkā-shən 

1

: an abnormal state that is essentially a poisoning

hypokalemia potentiates digoxin intoxication

—W. H. Abelmann et al.

no evidence of cocaine intoxication

—Margaret M. McCarron et al.

acute carbon monoxide intoxication

2

: the condition of being drunk : inebriation

Legal Definition

intoxication

noun

in·​tox·​i·​ca·​tion in-ˌtäk-sə-ˈkā-shən 

1

: the state or condition of being intoxicated

2

: a defense based on inability to form the requisite specific intent to commit a crime due to intoxication