intoxication

noun

in·​tox·​i·​ca·​tion in-ˌtäk-sə-ˈkā-shən 

1

a

: the condition of having physical or mental control markedly diminished by the effects of alcohol or drugs

drank to the point of intoxication

cocaine intoxication

b

: a strong excitement or elation

The mere knowledge that they are on an island, a little world entirely surrounded by the sea, fills them with an indescribable intoxication …

—Christine Osborne

2

: an abnormal state that is essentially a poisoning

carbon monoxide intoxication

Synonyms of intoxication

• alcoholism
• inebriation
• drunkenness
• inebriety

Examples of intoxication in a Sentence

there's a firm distinction between the moderate consumption of alcoholic beverages and overindulgence to the point of intoxication

the intoxication felt by two people who have just fallen in love

Recent Examples on the Web

After the primary autopsy, the coroner concluded Jackson's death was from acute Propofol intoxication, which caused the singer to go into cardiac arrest, NPR reported. —Alex Gurley, PEOPLE, 28 Apr. 2026

Indeed, the level of global acclaim Jackson, who tragically died in 2009 at the untimely age of 50 due to acute propofol intoxication, achieves is unprecedented. —Keith Murphy, VIBE.com, 24 Apr. 2026

The Ventura County Medical Examiner classified Hernandez's death as a homicide, caused by acute ethanol intoxication. —Julie Sharp, CBS News, 24 Apr. 2026

Jackson died of acute propofol intoxication on June 25, 2009, at age 50. —Patrick Ryan, USA Today, 23 Apr. 2026

Word History

First Known Use

1624, in the meaning defined at sense 1a

Rhymes for intoxication

• abbreviation
• abomination
• acceleration
• accentuation
• accommodation
• accreditation
• acculturation
• accumulation
• acetylation
• adjudication
• administration
• adulteration

Kids Definition

intoxication

noun

in·​tox·​i·​ca·​tion in-ˌtäk-sə-ˈkā-shən 

1

a

: an unhealthy state that is or is like a poisoning

carbon monoxide intoxication

b

: the condition of being drunk

2

: a strong excitement or elation

the intoxication of success

Medical Definition

intoxication

noun

in·​tox·​i·​ca·​tion in-ˌtäk-sə-ˈkā-shən 

1

: an abnormal state that is essentially a poisoning

hypokalemia potentiates digoxin intoxication

—W. H. Abelmann et al.

no evidence of cocaine intoxication

—Margaret M. McCarron et al.

acute carbon monoxide intoxication

2

: the condition of being drunk : inebriation

Legal Definition

intoxication

noun

in·​tox·​i·​ca·​tion in-ˌtäk-sə-ˈkā-shən 

1

: the state or condition of being intoxicated

2

: a defense based on inability to form the requisite specific intent to commit a crime due to intoxication