in·​ter·​sti·​tial | \ ˌin-tər-ˈsti-shəl How to pronounce interstitial (audio) \

Definition of interstitial

1 : occurring in or being an interval or intervening space or segment : of, relating to, or forming an interstice an interstitial space … the site has been running interstitial ads, which consist of a full page of advertising between editorial pages, for a little more than a year.— Carl Sullivan
2a : situated within but not restricted to or characteristic of a particular organ or tissue used especially of fibrous tissue
b : affecting the interstitial tissues of an organ or part interstitial cystitis
3 : being or relating to a crystalline compound in which usually small atoms or ions of a nonmetal occupy holes between the larger metal atoms or ions in the crystal lattice

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Other Words from interstitial

interstitially \ ˌin-​tər-​ˈsti-​shə-​lē How to pronounce interstitially (audio) \ adverb

Examples of interstitial in a Sentence

Recent Examples on the Web In the jargon of literary criticism, these in-between states are called interstitial – an interstice is a small space between something else, like the cracks in a sidewalk. Melissa Mohr, The Christian Science Monitor, "We’re in a ‘liminal’ moment, rather than ‘in limbo’," 11 June 2020 So much of 23 Hours to Kill could be pulled right out of the interstitial comedy-club scenes on his 30-year-old sitcom, and there’s joy in seeing an older pro still earning big laughs. David Sims, The Atlantic, "The Times Have Changed. Seinfeld Hasn’t.," 7 May 2020 Moore has been diagnosed with IBS, interstitial cystitis, GERD and gastroparesis, which all affect the digestive system. Matthew Vantryon, Indianapolis Star, "'I'm not being given a choice': As Indiana reopens, the most vulnerable hold their breath," 20 May 2020 GGOs in chest CT scans can also indicate congestive heart failure, inflammatory interstitial lung diseases, and diffuse alveolar hemorrhage (bleeding into the airspaces of the lungs), among other issues. Leah Groth,, "What Do 'Ground Glass Opacities' Mean in Lung Scans of COVID-19 Patients?," 16 Apr. 2020 Normally lymph comes from the interstitial tissues of the body. Lisa Sanders, New York Times, "He Had Trouble Breathing, and Inhalers Didn’t Help. What Was Going On?," 12 Feb. 2020 Thomas Lennon took the thankless job of delivering goofy wisecracks as winners approached the stage and also at interstitial moments. Troy Patterson, The New Yorker, "The Joyous, Fragmented, and Slightly Anxious 2019 Emmy Awards," 23 Sep. 2019 Collectively, these interstitial experiments show the cumulative effects of history and media on the inner life of an ordinary person. Matt Hanson, The New Yorker, "What John Dos Passos’s “1919” Got Right About 2019," 29 Dec. 2019 Gervais seemed to recede from the limelight as the show went on, appearing only for brief introductions to categories and interstitial one-liners. Daniel Arkin, NBC News, "Golden Globes 2020: The top moments from the ceremony," 6 Jan. 2020

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'interstitial.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of interstitial

1646, in the meaning defined at sense 1

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Time Traveler for interstitial

Time Traveler

The first known use of interstitial was in 1646

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Statistics for interstitial

Last Updated

22 Jun 2020

Cite this Entry

“Interstitial.” Dictionary, Merriam-Webster, Accessed 7 Jul. 2020.

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in·​ter·​sti·​tial | \ ˌint-ər-ˈstish-əl How to pronounce interstitial (audio) \

Medical Definition of interstitial

1 : situated within but not restricted to or characteristic of a particular organ or tissue used especially of fibrous tissue
2 : affecting the interstitial tissues of an organ or part interstitial hepatitis
3 : occurring in the part of a fallopian tube in the wall of the uterus interstitial pregnancy

Other Words from interstitial

interstitially \ -​ə-​lē How to pronounce interstitially (audio) \ adverb

More from Merriam-Webster on interstitial

Rhyming Dictionary: Words that rhyme with interstitial

Britannica English: Translation of interstitial for Arabic Speakers

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