in·​ter·​sti·​tial | \ ˌin-tər-ˈsti-shəl How to pronounce interstitial (audio) \

Definition of interstitial

1 : occurring in or being an interval or intervening space or segment : of, relating to, or forming an interstice an interstitial space … the site has been running interstitial ads, which consist of a full page of advertising between editorial pages, for a little more than a year.— Carl Sullivan
2a : situated within but not restricted to or characteristic of a particular organ or tissue used especially of fibrous tissue
b : affecting the interstitial tissues of an organ or part interstitial cystitis
3 : being or relating to a crystalline compound in which usually small atoms or ions of a nonmetal occupy holes between the larger metal atoms or ions in the crystal lattice

Other Words from interstitial

interstitially \ ˌin-​tər-​ˈsti-​shə-​lē How to pronounce interstitial (audio) \ adverb

Examples of interstitial in a Sentence

Recent Examples on the Web Bursts of musical joy could also be found at brief interstitial sets performed on a small side stage during the changeovers for main-stage performances. Stuart Munro,, 24 July 2022 Five years later, on the day of that chance meeting in Cambridge, Snyder had just returned from a trip to Los Angeles, where he was asked to produce interstitial animations for HBO. New York Times, 25 May 2022 That’s an anti-pattern because product management should be a special interstitial tissue connecting everyone in the organization. Stephen Hau, Forbes, 5 July 2022 Rothstein initially considered crafting interludes of opera for his film — Giuliani is a noted opera fan — but quickly realized the demands of mounting even an interstitial opera were too much. Jake Coyle, ajc, 10 June 2022 Editors Tracey Wadmore-Smith and Shayar Bhansali allow room for interstitial sequences that showcase the peaceful beauty of Los Angeles, from twinkling city lights to the jacaranda and palm trees sharing the landscape. Courtney Howard, Variety, 1 June 2022 My parents started the company in 1993 to help my mother’s sister, who suffered from interstitial cystitis. Jill Griffin, Forbes, 22 June 2022 The interstitial moments featuring Thede, Black, Gabrielle Dennis and Skye Townsend also get a new setting. Rick Porter, The Hollywood Reporter, 6 Apr. 2022 However, there will be interstitial ads during the show. Rs Editors, Rolling Stone, 13 Apr. 2022 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'interstitial.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of interstitial

1646, in the meaning defined at sense 1

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Time Traveler for interstitial

Time Traveler

The first known use of interstitial was in 1646

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Dictionary Entries Near interstitial



interstitial area

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Statistics for interstitial

Last Updated

10 Aug 2022

Cite this Entry

“Interstitial.” Dictionary, Merriam-Webster, Accessed 18 Aug. 2022.

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More Definitions for interstitial


in·​ter·​sti·​tial | \ ˌint-ər-ˈstish-əl How to pronounce interstitial (audio) \

Medical Definition of interstitial

1 : situated within but not restricted to or characteristic of a particular organ or tissue used especially of fibrous tissue
2 : affecting the interstitial tissues of an organ or part interstitial hepatitis
3 : occurring in the part of a fallopian tube in the wall of the uterus interstitial pregnancy

Other Words from interstitial

interstitially \ -​ə-​lē How to pronounce interstitial (audio) \ adverb

More from Merriam-Webster on interstitial

Britannica English: Translation of interstitial for Arabic Speakers


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