inotrope

noun
ino·​trope | \ ˈī-nə-ˌtrōp How to pronounce inotrope (audio) \

Definition of inotrope

: a substance that increases or decreases the force of muscular contractions : an inotropic drug or agent (such as epinephrine or a beta-blocker) Digoxin remains the only (albeit weak) positive inotrope that is valuable in the management of chronic heart failure.— C. R. Gibbs et al.

First Known Use of inotrope

1975, in the meaning defined above

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The first known use of inotrope was in 1975

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Cite this Entry

“Inotrope.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/inotrope. Accessed 22 Jan. 2021.

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More Definitions for inotrope

inotrope

noun
ino·​trope | \ ˈī-nə-ˌtrōp How to pronounce inotrope (audio) \

Medical Definition of inotrope

: an agent (such as epinephrine or a beta-blocker) that either increases or decreases the force of muscular contraction : an inotropic substance or drug In patients with advanced heart failure, medications called inotropes may be used to help the heart muscle beat more strongly.— Janet M. Torpy et al., The Journal of the American Medical Association, 13 June 2007 Agents that reduce intracellular calcium and inhibit contraction are called negative inotropes and include calcium channel blockers, parasympathomimetics, and states such as hypoxemia and metabolic acidosis.— Mary Gavaghan, AORN Journal, 1 Apr. 1998

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