Definition of inotrope
: an inotropic drug or agent (as epinephrine or a beta-blocker)
First Known Use of inotrope
Medical Definition of inotrope
: an agent (such as epinephrine or a beta-blocker) that either increases or decreases the force of muscular contraction : an inotropic substance or drug In patients with advanced heart failure, medications called inotropes may be used to help the heart muscle beat more strongly.—Janet M. Torpy et al., The Journal of the American Medical Association, 13 June 2007 Agents that reduce intracellular calcium and inhibit contraction are called negative inotropes and include calcium channel blockers, parasympathomimetics, and states such as hypoxemia and metabolic acidosis.—Mary Gavaghan, AORN Journal, 1 Apr. 1998
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