in·​oc·​u·​la·​tion | \ i-ˌnä-kyə-ˈlā-shən How to pronounce inoculation (audio) \

Definition of inoculation

1 : the act or process or an instance of inoculating especially : the introduction of a pathogen or antigen into a living organism to stimulate the production of antibodies
2 : inoculum

Examples of inoculation in a Sentence

Recent Examples on the Web

But most of that work has been on therapeutic inoculations—those tailored to combat a specific patient’s tumor. Keridwen Cornelius, Scientific American, "A Shot against Cancer Slated for Testing in Massive Dog Study," 7 June 2018 Too many investors forgot the lesson of the dot-com bubble of the late 1990s that being a darling of digital innovation isn’t inoculation against the classic dilemmas that afflict all young and fast-growing companies. The Editorial Board, WSJ, "Investors Unlike Facebook," 26 July 2018 Disgracefully, Franklin then mocked preacher Cotton Mather—a vociferous supporter of inoculation—after Mather lost a daughter and granddaughter to what might have been smallpox. Sam Kean, WSJ, "‘Young Benjamin Franklin’ Review: Poor Richard Sows His Oats," 17 Sep. 2018 After a measles outbreak that originated in Disneyland, California passed a tough inoculation law in 2015. Soumya Karlamangla,, "Leading vaccine skeptic Dr. Bob Sears put on probation by California medical board," 29 June 2018 Beppe Grillo, a comedian who was a founder of the Five Star Movement, argued in his comedy shows several years ago that vaccines should not be compulsory and that the inoculation of viruses can be dangerous. Gaia Pianigiani, New York Times, "Proof of Children’s Vaccinations? Italy Will Now Take Parents’ Word for It," 5 July 2018 As the physician who quickly became the coordinator of the World Health Organization’s efforts to roll out an experimental anti-Ebola inoculation in the DRC, he was needed on the ground. Dina Fine Maron, Scientific American, "How Ebola Vaccines Have Helped to Usher In a New Era in the Outbreak Response," 23 June 2018 The world’s first countywide inoculation against poliomyelitis was carried out in San Diego County., "April 17, 1955: S.D. MAKES WORLD POLIO HISTORY," 17 Apr. 2018 Smallpox inoculation had been well-established in the United States by the late 19th century, but occasional outbreaks continued. Brian Macquarrie,, "Winter weather helped uncover a dark past on Gallops Island," 3 May 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'inoculation.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of inoculation

1714, in the meaning defined at sense 1

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The first known use of inoculation was in 1714

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More Definitions for inoculation


in·​oc·​u·​la·​tion | \ i-ˌnä-kyə-ˈlā-shən How to pronounce inoculation (audio) \

Kids Definition of inoculation

: an act or instance of injecting a material (as a vaccine) into to protect against or treat a disease


in·​oc·​u·​la·​tion | \ in-ˌäk-yə-ˈlā-shən How to pronounce inoculation (audio) \

Medical Definition of inoculation

1 : the act or process or an instance of inoculating: as
a : the introduction of a microorganism into a medium suitable for its growth
b(1) : the introduction of a pathogen or antigen into a living organism to stimulate the production of antibodies
(2) : the introduction of a vaccine or serum into a living organism to confer immunity travelers in the tropics should have typhoid inoculations
2 : inoculum

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More from Merriam-Webster on inoculation

Rhyming Dictionary: Words that rhyme with inoculation

Spanish Central: Translation of inoculation

Nglish: Translation of inoculation for Spanish Speakers

Britannica English: Translation of inoculation for Arabic Speakers Encyclopedia article about inoculation

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