im·​mu·​no·​sup·​pres·​sion ˌi-myə-nō-sə-ˈpre-shən How to pronounce immunosuppression (audio)
: suppression (as by drugs or disease) of the immune response
Extreme caution must be exercised, however, in recipients of renal transplants because of immunosuppression and the susceptibility to infection.Rosalyn Kutcher et al.

Examples of immunosuppression in a Sentence

Recent Examples on the Web Those patients who were classified as having severe immunosuppression had a malignancy, or had a [bone marrow] transplant. Elizabeth Cooney, STAT, 24 Jan. 2024 But for patients who receive new kidneys, the transplant is often followed by severe lifelong challenges, many of which are linked to the immunosuppression drug regimen required after surgery to ensure the body does not reject the new organ. Annalisa Merelli, STAT, 2 Nov. 2023 Both subjects were on immunosuppression at the time.3 What to Know About Lantidra This drug was specifically approved to tackle ongoing and severe low blood sugar in patients with type 1 diabetes who are unable to reach target blood sugar levels despite intensive diabetes management and education. Laura Hensley, Verywell Health, 13 July 2023 But for Ken, long COVID was more than a year of inconsistent but extreme memory loss, extreme fatigue and immunosuppression that led to several emergency department visits. Emily Mendenhall, Scientific American, 12 May 2023 The next step, researchers say, is to use the same combination of genetic engineering and immunosuppression to fully replace a baboon heart with a pig heart. Carl Engelking, Discover Magazine, 30 Apr. 2014 Pancreas and Islet Cell Transplantation Transplantation surgery requires lifelong immunosuppression, which can complicate blood sugars and cause hyperglycemia. Verywell Health, 25 Feb. 2023 Three children who have undergone kidney transplants in California will likely be spared from ever having to take anti-rejection medication, because of an innovative technique that eliminates the need for lifelong immunosuppression, ground-breaking new research suggests. Erika Edwards, NBC News, 15 June 2022 The British government said Monday that children as young as 12 with severe neurodisabilities, Down syndrome, immunosuppression and multiple or severe learning disabilities, as well as those who are household contacts of individuals who are immunosuppressed, will be eligible for vaccination. Compiled Democrat-Gazette Staff From Wire Reports, Arkansas Online, 20 July 2021 See More

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'immunosuppression.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


immuno- + suppression

First Known Use

1963, in the meaning defined above

Time Traveler
The first known use of immunosuppression was in 1963

Dictionary Entries Near immunosuppression

Cite this Entry

“Immunosuppression.” Dictionary, Merriam-Webster, Accessed 26 Feb. 2024.

Medical Definition


im·​mu·​no·​sup·​pres·​sion -sə-ˈpresh-ən How to pronounce immunosuppression (audio)
: suppression (as by drugs or disease) of the immune response
Recurrent infection may develop in some patients despite minimization of their immunosuppression.Jay A. Fishman, The New England Journal of Medicine

More from Merriam-Webster on immunosuppression

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!