immune system

noun

: the bodily system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymph nodes, special deposits of lymphoid tissue (as in the gastrointestinal tract and bone marrow), macrophages, lymphocytes including the B cells and T cells, and antibodies

Examples of immune system in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Inflammation is the immune system’s response to fight against infection or disease. Merve Ceylan, Health, 26 Oct. 2025 For the virus, these are havens protected from the immune system. NPR, 24 Oct. 2025 The risk is highest for young children, frail or elderly people, and those with weakened immune systems. Emily Kay Votruba, EverydayHealth.com, 24 Oct. 2025 Medical experts say that REDs can damage an athlete’s metabolism, their immune system, their cardiovascular health, their menstrual cycle, and their mental health, as well as their athletic performance. George Ramsay, CNN Money, 23 Oct. 2025 See All Example Sentences for immune system

Word History

First Known Use

circa 1919, in the meaning defined above

Time Traveler
The first known use of immune system was circa 1919

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Cite this Entry

“Immune system.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/immune%20system. Accessed 29 Oct. 2025.

Kids Definition

immune system

noun
: the bodily system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymph nodes, lymphocytes, and antibodies

Medical Definition

immune system

noun
: the bodily system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymph nodes, special deposits of lymphoid tissue (as in the gastrointestinal tract and bone marrow), lymphocytes including the B cells and T cells, and antibodies

More from Merriam-Webster on immune system

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