immune system

noun

: the bodily system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymph nodes, special deposits of lymphoid tissue (as in the gastrointestinal tract and bone marrow), macrophages, lymphocytes including the B cells and T cells, and antibodies

Examples of immune system in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The immune system is directly connected to the gut, so consuming the right nutrients can positively affect both. — Sadie Chafe, FOXNews.com, 13 Oct. 2026 Multiple sclerosis is a disease that affects the central nervous system and is considered an autoimmune disease, in which the immune system attacks its own healthy cells. — Alexandra Skores, CNN Money, 12 Oct. 2026 Mice without flagellin receptors were less affected—indicating a direct link between flagellin and an immune system response. — Jackie Flynn Mogensen, Scientific American, 9 Oct. 2026 In the livers of urban fish, 425 genes in juveniles and 585 in adults showed activity largely linked to inflammation and immune system responses that was not seen in damselfish living in clean, untouched reef areas. — New Atlas, 9 Oct. 2026 See All Example Sentences for immune system

Word History

First Known Use

1899, in the meaning defined above

Time Traveler
The first known use of immune system was in 1899

Browse Nearby Words

Cite this Entry

“Immune system.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/immune%20system. Accessed 17 Oct. 2026.

Kids Definition

immune system

noun
: the bodily system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymph nodes, lymphocytes, and antibodies

Medical Definition

immune system

noun
: the bodily system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymph nodes, special deposits of lymphoid tissue (as in the gastrointestinal tract and bone marrow), lymphocytes including the B cells and T cells, and antibodies

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