hypothalamic

adjective

hy·​po·​tha·​lam·​ic ˌhī-pō-thə-ˈla-mik 

: of or relating to the hypothalamus

hypothalamic neurons

Examples of hypothalamic in a Sentence

Recent Examples on the Web

However, some people have no nasal cycle (such as those who have a hypothalamic disorder). — Adam Taylor, CNN Money, 8 Mar. 2026

Schulte and May say that a hypothalamic origin of migraines would help to explain some of the symptoms of the disorder, such as changes in appetite, that often accompany the headaches. — Neuroskeptic, Discover Magazine, 22 May 2016

Although hypothalamic dysfunction can trigger dozens of other symptoms, the hallmark signs are insomnia (despite exhaustion), brain fog and widespread pain, the doctor said. — Shiv Sudhakar, FOXNews.com, 20 Dec. 2025

The neural circuitry involved in a hiccup episode includes the vagus nerve, the phrenic nerve, the medulla oblongata and the hypothalamic reticular formation. — Scott Travers, Forbes.com, 22 Apr. 2026

Adaptogens work primarily by modulating the hypothalamic-pituitary-adrenal axis — the system that governs your stress hormones — and balancing cortisol. — Lauren Schuster, Miami Herald, 27 May 2026

Anxiety Relief and Depression Magnesium regulates the hypothalamic pituitary adrenal axis (HPAA), which is involved in the body’s stress response. — Amy Brownstein, Ms, Rdn, Verywell Health, 13 Jan. 2025

Its entire sensor architecture exists to model the HPO axis—the hypothalamic-pituitary-ovarian system, the hormonal feedback loop that governs nearly every dimension of female physiology. — Lily Mae Lazarus, Fortune, 17 June 2026

One protein, dubbed ADM, particularly stood out with high levels known to play a role in both the sympathetic nervous system (SNS) and hypothalamic–pituitary–adrenal (HPA) activity. — Rich Haridy, New Atlas, 22 Jan. 2025

Word History

Etymology

hypothalamus + -ic entry 1

First Known Use

1899, in the meaning defined above

Rhymes for hypothalamic

• aerodynamic
• geodynamic
• haemodynamic
• hemodynamic
• hydrodynamic
• photodynamic
• psychodynamic
• spinothalamic
• thermodynamic
• ceramic
• dynamic
• thalamic

Medical Definition

hypothalamic

adjective

hy·​po·​tha·​lam·​ic ˌhī-pō-thə-ˈlam-ik 

: of or relating to the hypothalamus

hypothalamically

-i-k(ə-)lē 

adverb