hypervariable

adjective hy·per·var·i·able \ ˌhī-pər-ˈver-ē-ə-bəl \

Definition of hypervariable

: relating to or being any of the relatively short extremely variable polypeptide chain segments in the light chain or heavy chain of an antibody; also : relating to, containing, or being a highly variable nucleotide sequence

First Known Use of hypervariable

1970

in the meaning defined above

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Medical Dictionary

hypervariable

adjective hy·per·vari·able \ -ˈver-ē-ə-bəl, -ˈvar- \

medical Definition of hypervariable

: relating to or being any of the relatively short polypeptide chain segments in the variable region of an antibody light chain or heavy chain that are extremely variable in the sequence of their amino acid residues and that determine the conformation and specificity of the site which recognizes and combines with an antigen; also : relating to, containing, or being a highly variable nucleotide sequence

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