hypermutable

adjective hy·per·mu·ta·ble \ ˌhī-pər-ˈmyü-tə-bəl \
Updated on: 15 Nov 2017

Definition of hypermutable

: exhibiting or capable of excessive mutation or change
  • Only the hypermutable cells that subsequently achieve a beneficial mutation would survive; the others would cease to be viable.
  • —John Rennie
  • Another severe obstacle for those with compromised immune systems: the hypermutable bacteria that can be found in cystic fibrosis patients. These chameleon-like germs produce numerous mutations when they replicate, creating more potential possibilities for drug resistance.
  • —Jim Doyle

hypermutability

play \ˌhī-pər-ˌmyü-tə-ˈbi-lə-tē\ noun
    • "What we've found is a subtle alteration in the genetic code that causes DNA instability and leads to hypermutability, or a cascade of mutations in surrounding genes …"
    • —Kenneth Kinzler

First Known Use of hypermutable

1959


Medical Dictionary

hypermutable

adjective hy·per·mu·ta·ble \ -ˈmyüt-ə-bəl \

medical Definition of hypermutable

: exhibiting or capable of excessive mutation or change
  • Another severe obstacle for those with compromised immune systems: the hypermutable bacteria that can be found in cystic fibrosis patients. These chameleon-like germs produce numerous mutations when they replicate, creating more potential possibilities for drug resistance.
  • —Jim DoyleThe Birmingham (Alabama) News9 Oct. 2013

hypermutability

play \-ˌmyüt-ə-ˈbil-ət-ē\ noun
    • “What we've found,” he [Kenneth Kinzler] explained, “is a subtle alteration in the genetic code that causes DNA instability and leads to hypermutability, or a cascade of mutations in surrounding genes.”
    • Newsday (Melville, New York)26 Aug. 1997

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