hydrochloride

noun

hy·​dro·​chlo·​ride ˌhī-drə-ˈklȯr-ˌīd 

: a chemical complex composed of an organic base (such as an alkaloid) in association with hydrogen chloride

Examples of hydrochloride in a Sentence

Recent Examples on the Web

Creatine hydrochloride is often marketed as more bioavailable than creatine monohydrate, meaning your body absorbs it more easily. —Jillian Kubala, Health, 21 Apr. 2025

Hydroxyzine hydrochloride is available as a:2 Tablet Oral solution Intramuscular injection Hydroxyzine pamoate is available as a capsule. —Jessica Swirble, Verywell Health, 11 Feb. 2025

One of its products is naloxone hydrochloride, used for emergency treatment of opioid overdoses. —John Dorfman, Forbes, 17 Mar. 2025

The main difference between hydrochloride and pamoate is the dosage form. —Jessica Swirble, Verywell Health, 11 Feb. 2025

Word History

First Known Use

1826, in the meaning defined above

Phrases Containing hydrochloride

• cetirizine hydrochloride

Rhymes for hydrochloride

• amiloride
• hexachloride
• oxychloride
• pentachloride
• tetrachloride
• bichloride
• dichloride
• perchloride
• trichloride
• boride
• chloride
• dihydrochloride

Medical Definition

hydrochloride

noun

hy·​dro·​chlo·​ride -ˈklō(ə)r-ˌīd, -ˈklȯ(ə)r- 

: a salt of hydrochloric acid with an organic base used especially as a vehicle for the administration of a drug