hy·​dro·​chlo·​ride | \ ˌhī-drə-ˈklȯr-ˌīd How to pronounce hydrochloride (audio) \

Definition of hydrochloride

: a chemical complex composed of an organic base (such as an alkaloid) in association with hydrogen chloride

Examples of hydrochloride in a Sentence

Recent Examples on the Web

But there are medications meant to relieve UTI symptoms while the infection clears, such as Azo, which contains the active ingredient phenazopyridine hydrochloride. Korin Miller, SELF, "4 Causes Behind Urine So Foamy It Could Top a Beer," 4 Oct. 2018 The main ingredient in that fast-acting antihistamine is diphenhydramine hydrochloride (DPH). Carolyn L. Todd, SELF, "How Bad Is It to Take an Antihistamine to Sleep Every Night?," 13 Dec. 2018 Although phenazopyridine hydrochloride is most famous for causing orange pee, some people also report foamy urine, Dr. Ramin says, adding that this seems to be a chemical reaction that happens when the drug mixes with water. Korin Miller, SELF, "4 Causes Behind Urine So Foamy It Could Top a Beer," 4 Oct. 2018 Bonjesta contains doxylamine succinate (an antihistamine found in over-the-counter sleep aids) and pyridoxine hydrochloride (the chemical name for a form of vitamin B6), which are the same active ingredients found in Diclegis. Korin Miller, SELF, "What to Know About Bonjesta, the Morning Sickness Drug Kim Kardashian Is Posting About on Instagram," 28 June 2018 Naloxone hydrochloride is used for the complete or partial reversal of a confirmed or suspected opioid overdose. Mary Bernard, Philly.com, "Opioid overdose antidote Naloxone recalled nationwide," 5 June 2018 Lucemyra, also known as lofexidine hydrochloride, was originally intended to be a hypertension medication. Karen Kaplan, latimes.com, "FDA approves Lucemyra to treat symptoms of opioid withdrawal and help patients overcome addiction," 16 May 2018 The officer reportedly found 17 hydroxyzine hydrochloride pills and a cigarillo containing marijuana during a vehicle search. Jennifer James, Houston Chronicle, "Friendswood: Narcotics arrests top police report," 29 Mar. 2018 While running from police, Dalton threw aside a bag of narcotics that contained 49 grams of methamphetamine, 51 grams of cocaine hydrochloride, 23 grams of heroin, 16 grams of crack cocaine and 29 grams of marijuana, according to investigators. Laurel Andrews, Anchorage Daily News, "Man sentenced to 15 years on drug charges after Anchorage police found him asleep at the wheel," 14 Mar. 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'hydrochloride.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

See More

First Known Use of hydrochloride

1826, in the meaning defined above

Keep scrolling for more

Learn More about hydrochloride

Statistics for hydrochloride

Look-up Popularity

Time Traveler for hydrochloride

The first known use of hydrochloride was in 1826

See more words from the same year

Keep scrolling for more

More Definitions for hydrochloride


hy·​dro·​chlo·​ride | \ -ˈklō(ə)r-ˌīd, -ˈklȯ(ə)r- How to pronounce hydrochloride (audio) \

Medical Definition of hydrochloride

: a salt of hydrochloric acid with an organic base used especially as a vehicle for the administration of a drug

Comments on hydrochloride

What made you want to look up hydrochloride? Please tell us where you read or heard it (including the quote, if possible).


not to be persuaded, moved, or stopped

Get Word of the Day daily email!

Test Your Vocabulary

Words from Greek and Latin Quiz

  • roman forum
  • Which of the following months comes from a Latin word for “ten”?
Spell It

Can you spell these 10 commonly misspelled words?


Test Your Knowledge - and learn some interesting things along the way.

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!