First Known Use of cetirizine
Medical Definition of cetirizine
: a long-acting, nonsedating, antihistamine drug taken orally in the form of its dihydrochloride C21H25ClN2O3·2HCl to treat allergic rhinitis and chronic hives ◆Cetirizine is a derivative of piperazine and an H1 antagonist that binds competitively with histamine to H1 receptors on cell membranes. It is marketed under the trademark Zyrtec.
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