an·ti·his·ta·mine | \-ˈhis-tə-ˌmēn, -mən\

Definition of antihistamine 

: any of various compounds that counteract histamine in the body and that are used for treating allergic reactions (such as hay fever) and cold symptoms

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Other Words from antihistamine

antihistamine adjective
antihistaminic \-ˌhis-tə-ˈmi-nik \ adjective or noun

Examples of antihistamine in a Sentence

Recent Examples on the Web

Bonjesta contains doxylamine succinate (an antihistamine found in over-the-counter sleep aids) and pyridoxine hydrochloride (the chemical name for a form of vitamin B6), which are the same active ingredients found in Diclegis. Korin Miller, SELF, "What to Know About Bonjesta, the Morning Sickness Drug Kim Kardashian Is Posting About on Instagram," 28 June 2018 There are conventional medications for morning sickness that are considered safe for pregnancy, such as vitamin B6 and doxylamine, an antihistamine sold under brands like Unisom. Michael Nedelman, CNN, "Cannabis dispensaries recommend products to pregnant women," 10 May 2018 If that doesn’t help, things like antihistamines and allergy shots might minimize your symptoms—talk to your doctor to figure out what makes the most sense. Korin Miller, SELF, "9 Health Issues That Can Cause Sensitivity to Light," 5 June 2018 Once at the hospital, The Honeydogs singer was treated with an IV and given steroids and antihistamines to stop the swelling. Samantha Brodsky, Good Housekeeping, "Dad Suffers Second-Degree Burns From Lime Juice," 7 July 2017 An antihistamine or anti-itch creams like hydrocortisone can also help. Caroline Picard, Good Housekeeping, "This Is the Only Thing You Should Do If a Bee Stings You," 6 June 2017 Seroquel works like an antihistamine at low doses, with mild sedation as a side effect. Amy Ellis Nutt, Washington Post, "One of America’s most popular drugs — first aimed at schizophrenia — reveals the issues of ‘off-label’ use," 30 Mar. 2018 Low-sedating antihistamines are available in many generic forms, as well as such brand names as Allegra and Zyrtec. Maureen Langley, Post-Tribune, "Experts: Indiana's allergy season worse than usual this year," 3 July 2018 The rash often can be treated with hydrocortisone and antihistamine creams available at most drug stores, according to the Florida Department of Health. Michelle Ewing, ajc, "Sea lice in Florida? Beachgoers warned about itch-inducing pests," 28 June 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'antihistamine.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of antihistamine

1933, in the meaning defined above

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Last Updated

26 Sep 2018

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Time Traveler for antihistamine

The first known use of antihistamine was in 1933

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More Definitions for antihistamine



English Language Learners Definition of antihistamine

medical : a drug that is used to treat allergic reactions and colds


an·ti·his·ta·mine | \ˌant-i-ˈhis-tə-ˌmēn, ˌan-ˌtī-, -mən \

Medical Definition of antihistamine 

(Entry 1 of 2)

: tending to block or counteract the physiological action of histamine human blood lacks antihistamine activity



Medical Definition of antihistamine (Entry 2 of 2)

: any of various compounds that oppose the actions of histamine and are used especially for treating allergic reactions (as hay fever), cold symptoms, and motion sickness

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Comments on antihistamine

What made you want to look up antihistamine? Please tell us where you read or heard it (including the quote, if possible).


exaggeratedly or childishly emotional

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