ho·​mo·​zy·​gous | \ ˌhō-mə-ˈzī-gəs How to pronounce homozygous (audio) , ˌhä- \

Definition of homozygous

: having the two genes at corresponding loci on homologous chromosomes identical for one or more loci

Keep scrolling for more

Other Words from homozygous

homozygously adverb

Examples of homozygous in a Sentence

Recent Examples on the Web People homozygous for 35delG, like Yevgenievna’s daughter, will inevitably have hearing loss, albeit to varying degrees. Jon Cohen, Science | AAAS, "Deaf couple may edit embryo’s DNA to correct hearing mutation," 21 Oct. 2019 Cooper’s jerboa project could easily turn out to need mice homozygous for 10 or more genes. Quanta Magazine, "Gene Drives Work in Mice (if They’re Female)," 23 Jan. 2019 My wife is homozygous non-risk, for the FTO obesity region. Nestor Ramos, BostonGlobe.com, "Will my genes doom my young daughter to a weight problem?," 31 Jan. 2018 At this stage Complete has validated a set of 57 homozygous insertion/deletion variants, all of which were called accurately by their platform, but this is far too small a data-set to be extrapolating to genome-wide error rates. Daniel Macarthur, WIRED, "Broad Institute to use Complete Genomics to sequence genomes of cancer patients," 3 Mar. 2009

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'homozygous.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

See More

First Known Use of homozygous

1902, in the meaning defined above

Keep scrolling for more

Learn More about homozygous

Time Traveler for homozygous

Time Traveler

The first known use of homozygous was in 1902

See more words from the same year

Statistics for homozygous

Last Updated

27 Nov 2019

Cite this Entry

“Homozygous.” The Merriam-Webster.com Dictionary, Merriam-Webster Inc., https://www.merriam-webster.com/dictionary/homozygous?pronunciation&lang=en_us&dir=h&file=homozy04. Accessed 15 December 2019.

Keep scrolling for more

More Definitions for homozygous


ho·​mo·​zy·​gous | \ -ˈzī-gəs How to pronounce homozygous (audio) \

Medical Definition of homozygous

: having the two genes at corresponding loci on homologous chromosomes identical for one or more loci — compare heterozygous

Other Words from homozygous

homozygously adverb

More from Merriam-Webster on homozygous

Rhyming Dictionary: Words that rhyme with homozygous

Comments on homozygous

What made you want to look up homozygous? Please tell us where you read or heard it (including the quote, if possible).


delight or enjoyment

Get Word of the Day daily email!

Test Your Vocabulary

Great Scrabble Words—A Quiz

  • scrabble tiles that read scrabble quiz
  • Which of the following Q-without-U words means the number five in cards or dice?
Spell It

Can you spell these 10 commonly misspelled words?

Syn City

Test Your Knowledge - and learn some interesting things along the way.

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!