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And this gene, unlike its more deterministic cousins, is not really rare at all; 2 percent of the U.S. population are APOE4 homozygotes.—Laura Hercher, Scientific American, 1 Aug. 2024 The findings suggest that people with two copies of the gene—who are called APOE4 homozygotes—have a distinct genetic form of Alzheimer’s.—Will Sullivan, Smithsonian Magazine, 7 May 2024 Analyzing data from more than 13,000 people, researchers found that among APOE4 homozygotes, people who carry two copies of the gene variant, nearly all showed biological signs of Alzheimer’s in the brain.—Elaine Chen Reprints, STAT, 7 May 2024 Interestingly the persistent individual in the Longar location also a homozygote.—Razib Khan, Discover Magazine, 16 Jan. 2012
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