: one haploid set of chromosomes with the genes they contain
broadly
: the genetic material of an organism compare proteome
Examples of genome in a Sentence
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Scientists made 15 exact genetic edits to the gray wolf genome in order to create the new wolves that look like dire wolves.
—
Joseph Wilkinson, New York Daily News, 8 Apr. 2025
These two wolves were brought back from extinction using genetic edits derived from a complete dire wolf genome, meticulously reconstructed by Colossal from ancient DNA found in fossils dating back 11,500 and 72,000 years.
—Samantha Bergeson, IndieWire, 8 Apr. 2025
The Colossal team thus engineered two other genes that shut down black and red pigmentation, leading to the dire wolf’s characteristic light color without causing any harm in the edited gray wolf genome.
—Jeffrey Kluger, Time, 7 Apr. 2025
But the dire wolf’s genome is still almost identical to that of the gray wolf.
—Emily Mullin, Wired News, 7 Apr. 2025
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Joseph Wilkinson, New York Daily News, 8 Apr. 2025
These two wolves were brought back from extinction using genetic edits derived from a complete dire wolf genome, meticulously reconstructed by Colossal from ancient DNA found in fossils dating back 11,500 and 72,000 years.
—Samantha Bergeson, IndieWire, 8 Apr. 2025
The Colossal team thus engineered two other genes that shut down black and red pigmentation, leading to the dire wolf’s characteristic light color without causing any harm in the edited gray wolf genome.
—Jeffrey Kluger, Time, 7 Apr. 2025
But the dire wolf’s genome is still almost identical to that of the gray wolf.
—Emily Mullin, Wired News, 7 Apr. 2025
See All Example Sentences for genome
Cite this Entry
“Genome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/genome. Accessed 4 May. 2025.
Copy CitationMedical Definition
genome
noun
ge·nome
ˈjē-ˌnōm 
: one haploid set of chromosomes with the genes they contain
broadly
: the genetic material of an organism
The idea behind sequencing an organism's genome—decoding, letter by letter, the message contained in every last one of its genes—is that it would tell us a lot about how the organism works. —Lori Oliwenstein, Discover
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