genome

noun

ge·​nome ˈjē-ˌnōm 

: one haploid set of chromosomes with the genes they contain

broadly : the genetic material of an organism compare proteome

Examples of genome in a Sentence

Recent Examples on the Web

The clinical stage genome editing company plunged 45% after pausing patient dosing and screening for its MAGNITUDE and MAGNITUDE-2 Phase 3 clinical trials. —Scott Schnipper, CNBC, 27 Oct. 2025

Researchers at the tech giant created DeepSomatic, a new open-source AI model that helps scientists analyze cancer genomes more quickly and accurately. —Jeremy Kahn, Fortune, 21 Oct. 2025

In this op-ed, Andrew Hessel, cofounder of the Human Genome Project–write, argues that genome writing is humanity’s next great moonshot, outlining how DNA synthesis could transform biology, medicine, and industry. —Big Think, 20 Oct. 2025

This part of the study provided the first direct functional proof that mutations within the phage genome can permanently silence its ability to reactivate. —New Atlas, 16 Oct. 2025

Word History

Etymology

German Genom, from Gen gene + -om (as in Chromosom chromosome)

First Known Use

1926, in the meaning defined above

Phrases Containing genome

• genome editing

Rhymes for genome

• biome
• megohm
• nichrome
• noisome
• prodrome
• radome
• rhizome
• shalom
• syndrome
• acrosome
• aerodrome
• catacomb

Medical Definition

genome

noun

ge·​nome ˈjē-ˌnōm 

: one haploid set of chromosomes with the genes they contain

broadly : the genetic material of an organism

The idea behind sequencing an organism's genome—decoding, letter by letter, the message contained in every last one of its genes—is that it would tell us a lot about how the organism works.

—Lori Oliwenstein, Discover