genome

noun

ge·​nome ˈjē-ˌnōm How to pronounce genome (audio)
: one haploid set of chromosomes with the genes they contain
broadly : the genetic material of an organism compare proteome

Examples of genome in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The intriguing finding, published Thursday in the journal Science, could help explain why the Neanderthal ancestry that is present in humans today is unevenly distributed across the genome. Katie Hunt, CNN Money, 26 Feb. 2026 Free-living non-native pigs east of the Wallace Line exhibit complex genomes that suggest waves of prehistoric human translocations. Rafil Kroll-Zaidi, Harpers Magazine, 24 Feb. 2026 What may actually be surprising is that cats and humans share about 90 percent of their respective genomes. K. R. Callaway, Scientific American, 19 Feb. 2026 The team identified a region in the banana genome that controls resistance to a strain of Fusarium wilt called Sub Tropical Race 4 (STR4), which affects bananas in subtropical regions. Laura Baisas, Popular Science, 19 Feb. 2026 See All Example Sentences for genome

Word History

Etymology

German Genom, from Gen gene + -om (as in Chromosom chromosome)

First Known Use

1926, in the meaning defined above

Time Traveler
The first known use of genome was in 1926

Browse Nearby Words

Cite this Entry

“Genome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/genome. Accessed 3 Mar. 2026.

Medical Definition

genome

noun
ge·​nome ˈjē-ˌnōm How to pronounce genome (audio)
: one haploid set of chromosomes with the genes they contain
broadly : the genetic material of an organism
The idea behind sequencing an organism's genome—decoding, letter by letter, the message contained in every last one of its genes—is that it would tell us a lot about how the organism works. Lori Oliwenstein, Discover

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