: one haploid set of chromosomes with the genes they contain
broadly
: the genetic material of an organism compare proteome
Examples of genome in a Sentence
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In 2024, the Collin County Medical Examiner’s Office sent forensic evidence to Othram’s laboratory near Houston, where scientists used forensic-grade genome sequencing to build the woman’s genetic profile, officials said.
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Lillie Davidson, Fort Worth Star-Telegram, 6 Sep. 2025
Mazzei's ruling pointed out that whole genome sequencing was also used to solve the 1982 cold case rape and murder of 9-year-old Daralyn Johnson in Idaho, resulting in two consecutive life sentences for David Allen Dalrymple.
—N'dea Yancey-Bragg, USA Today, 3 Sep. 2025
Heuermann’s defense attorney Michael Brown had argued the DNA technology, known as whole genome sequencing, has not yet been widely accepted by the scientific community and therefore shouldn’t be permitted.
—Mark Morales, CNN Money, 3 Sep. 2025
To test where this compound came from, Mulligan analyzed 115 animal genomes to look for evidence when coprostane-producing enzymes first evolved.
—David Bressan, Forbes.com, 30 Aug. 2025
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Lillie Davidson, Fort Worth Star-Telegram, 6 Sep. 2025
Mazzei's ruling pointed out that whole genome sequencing was also used to solve the 1982 cold case rape and murder of 9-year-old Daralyn Johnson in Idaho, resulting in two consecutive life sentences for David Allen Dalrymple.
—N'dea Yancey-Bragg, USA Today, 3 Sep. 2025
Heuermann’s defense attorney Michael Brown had argued the DNA technology, known as whole genome sequencing, has not yet been widely accepted by the scientific community and therefore shouldn’t be permitted.
—Mark Morales, CNN Money, 3 Sep. 2025
To test where this compound came from, Mulligan analyzed 115 animal genomes to look for evidence when coprostane-producing enzymes first evolved.
—David Bressan, Forbes.com, 30 Aug. 2025
See All Example Sentences for genome
Cite this Entry
“Genome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/genome. Accessed 9 Sep. 2025.
Copy CitationMedical Definition
genome
noun
ge·nome
ˈjē-ˌnōm 
: one haploid set of chromosomes with the genes they contain
broadly
: the genetic material of an organism
The idea behind sequencing an organism's genome—decoding, letter by letter, the message contained in every last one of its genes—is that it would tell us a lot about how the organism works. —Lori Oliwenstein, Discover
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