genome

noun

ge·​nome ˈjē-ˌnōm 

: one haploid set of chromosomes with the genes they contain

broadly : the genetic material of an organism compare proteome

Examples of genome in a Sentence

Recent Examples on the Web

Using forensic-grade genome sequencing, investigators developed a genealogical profile that produced new leads. —Cbs News Atlanta Digital Team, CBS News, 17 Mar. 2026

That leaves the remaining genome — the vast majority of it — as Gray wolf. —Hanna Wickes, Charlotte Observer, 16 Mar. 2026

In 2019, Spanish geneticists mapped the genomes of bitter and sweet almonds and determined that a single gene was responsible for almond bitterness. —Joshua Siskin, Oc Register, 14 Mar. 2026

But what if the larvae are dead or missing, there’s no high-quality DNA or there isn’t the time—or equipment—to sequence the flies’ genomes? —Rohini Subrahmanyam, Scientific American, 10 Mar. 2026

Word History

Etymology

German Genom, from Gen gene + -om (as in Chromosom chromosome)

First Known Use

1926, in the meaning defined above

Phrases Containing genome

• genome editing

Rhymes for genome

• biome
• megohm
• nichrome
• noisome
• prodrome
• radome
• rhizome
• shalom
• syndrome
• acrosome
• aerodrome
• catacomb

Medical Definition

genome

noun

ge·​nome ˈjē-ˌnōm 

: one haploid set of chromosomes with the genes they contain

broadly : the genetic material of an organism

The idea behind sequencing an organism's genome—decoding, letter by letter, the message contained in every last one of its genes—is that it would tell us a lot about how the organism works.

—Lori Oliwenstein, Discover