genome

noun

ge·​nome ˈjē-ˌnōm 

: one haploid set of chromosomes with the genes they contain

broadly : the genetic material of an organism compare proteome

Examples of genome in a Sentence

Recent Examples on the Web

And all of these projects rely on advances in computational biology, using AI to compare genomes of different species and also to intuit and fill in the gaps of ancient DNA. —Alex Morris, Rolling Stone, 19 May 2026

Their first step involved gathering all 470 flowering plant genomes that have been sequenced, a mix of wild species and agricultural crops from all over the world. —Ari Daniel, NPR, 19 May 2026

Most clinics start with comprehensive evaluations that can include CT, MRI and DXA scans, blood panels, cognitive testing, fitness assessments and genome sequencing. —Hanna Wickes, Fort Worth Star-Telegram, 19 May 2026

Initial workups at longevity clinics commonly include CT, MRI and DXA scans, blood panels, cognitive testing, fitness assessments and genome sequencing. —Hanna Wickes, Sacbee.com, 19 May 2026

Word History

Etymology

German Genom, from Gen gene + -om (as in Chromosom chromosome)

First Known Use

1926, in the meaning defined above

Phrases Containing genome

• genome editing

Rhymes for genome

• biome
• nichrome
• noisome
• prodrome
• radome
• rhizome
• shalom
• syndrome
• acrosome
• aerodrome
• catacomb
• centrosome

Medical Definition

genome

noun

ge·​nome ˈjē-ˌnōm 

: one haploid set of chromosomes with the genes they contain

broadly : the genetic material of an organism

The idea behind sequencing an organism's genome—decoding, letter by letter, the message contained in every last one of its genes—is that it would tell us a lot about how the organism works.

—Lori Oliwenstein, Discover