genome

noun

ge·​nome ˈjē-ˌnōm 

: one haploid set of chromosomes with the genes they contain

broadly : the genetic material of an organism compare proteome

Examples of genome in a Sentence

Recent Examples on the Web

Avalo uses machine learning to analyze the cotton genome and identify combinations associated with traits such as heat tolerance, water and nitrogen efficiency, yield, fiber length and fiber strength. — Alexandra Harrell, Footwear News, 27 Aug. 2026

Now, researchers have developed a new method to analyze modern human genomes and uncovered evidence of two previously unknown ancestral lineages by working backward from DNA in living people to reconstruct missing parts of the human family tree. — Taylor Nicioli, CNN Money, 26 Aug. 2026

In the genome, part of most genes is dedicated to encoding a protein. — ArsTechnica, 26 Aug. 2026

The rest of the genome, along with the rest of the family, matters as well. — William A. Haseltine, Forbes.com, 20 Aug. 2026

Word History

Etymology

German Genom, from Gen gene + -om (as in Chromosom chromosome)

First Known Use

1926, in the meaning defined above

Phrases Containing genome

• genome editing

Rhymes for genome

• biome
• nichrome
• noisome
• prodrome
• radome
• rhizome
• shalom
• syndrome
• acrosome
• aerodrome
• catacomb
• centrosome

Medical Definition

genome

noun

ge·​nome ˈjē-ˌnōm 

: one haploid set of chromosomes with the genes they contain

broadly : the genetic material of an organism

The idea behind sequencing an organism's genome—decoding, letter by letter, the message contained in every last one of its genes—is that it would tell us a lot about how the organism works.

—Lori Oliwenstein, Discover