genome

noun

ge·​nome ˈjē-ˌnōm How to pronounce genome (audio)
: one haploid set of chromosomes with the genes they contain
broadly : the genetic material of an organism compare proteome

Examples of genome in a Sentence

Recent Examples on the Web
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Those samples will also be used to create whole genome sequences for each of these species. John Timmer, ArsTechnica, 25 June 2026 Relatively speaking, the least controversial application of human embryo genome editing is to use it to try to prevent transmission of genetic diseases. Paul Knoepfler, STAT, 24 June 2026 When the results came back from a genome sequencing laboratory, they were handed off to FHD Forensics, a company that matches DNA with historical genealogy records to identify unknown human remains. Scott Neuman, NPR, 23 June 2026 And perhaps more to the point, the genome might not submit to the kind of straightforward input-output approach that such AI models ultimately assume. Philip Ball, Quanta Magazine, 18 June 2026 See All Example Sentences for genome

Word History

Etymology

German Genom, from Gen gene + -om (as in Chromosom chromosome)

First Known Use

1926, in the meaning defined above

Time Traveler
The first known use of genome was in 1926

Browse Nearby Words

Cite this Entry

“Genome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/genome. Accessed 30 Jun. 2026.

Medical Definition

genome

noun
ge·​nome ˈjē-ˌnōm How to pronounce genome (audio)
: one haploid set of chromosomes with the genes they contain
broadly : the genetic material of an organism
The idea behind sequencing an organism's genome—decoding, letter by letter, the message contained in every last one of its genes—is that it would tell us a lot about how the organism works. Lori Oliwenstein, Discover

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