genome

noun

ge·​nome ˈjē-ˌnōm How to pronounce genome (audio)
: one haploid set of chromosomes with the genes they contain
broadly : the genetic material of an organism compare proteome

Examples of genome in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Fortunately, today, researchers explained that recent advancements in paleogenomics have permitted this cross-examination between modern genomes and ancient DNA, Archaeology Mag reports. Maria Mocerino, Interesting Engineering, 21 Dec. 2025 By checking fragments of DNA in a sample against a library of fish genomes, Parsons and Van Cise can identify the exact species a whale ate over a roughly 24-hour period and in what relative amounts—for instance, 60 percent Chinook salmon, 30 percent chum salmon, 10 percent halibut. Kelso Harper, Scientific American, 16 Dec. 2025 Beethoven’s genome has been made publicly available, and a 2024 study revealed that the composer experienced lead poisoning, as well as elevated levels of arsenic and mercury. Ashley Strickland, CNN Money, 12 Dec. 2025 However, new genome sequencing data reveals an unexpected twist to this long evolutionary story. David Toews, The Conversation, 11 Dec. 2025 See All Example Sentences for genome

Word History

Etymology

German Genom, from Gen gene + -om (as in Chromosom chromosome)

First Known Use

1926, in the meaning defined above

Time Traveler
The first known use of genome was in 1926

Browse Nearby Words

Cite this Entry

“Genome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/genome. Accessed 24 Dec. 2025.

Medical Definition

genome

noun
ge·​nome ˈjē-ˌnōm How to pronounce genome (audio)
: one haploid set of chromosomes with the genes they contain
broadly : the genetic material of an organism
The idea behind sequencing an organism's genome—decoding, letter by letter, the message contained in every last one of its genes—is that it would tell us a lot about how the organism works. Lori Oliwenstein, Discover

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