genome

noun

ge·​nome ˈjē-ˌnōm How to pronounce genome (audio)
: one haploid set of chromosomes with the genes they contain
broadly : the genetic material of an organism compare proteome

Examples of genome in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The data on genomes that are cached in the museum will be open-sourced, providing researchers and geneticists around the world with information on all 10,000 species, in pursuit of conservation or de-extinction projects similar to what Colossal achieved with the dire wolf. Jeffrey Kluger, Time, 4 Feb. 2026 Even so, the model is helping scientists to prioritize which genetic variants are most likely to matter, narrowing the search from across the genome to a manageable set of testable hypotheses. Elie Dolgin, IEEE Spectrum, 4 Feb. 2026 After the first dairy cow’s genome was sequenced in 2009, the industry started raising the genetic ceiling. Sarah Zhang, The Atlantic, 4 Feb. 2026 In an email, Jong-Hwei Su Pang, a professor at Chang Gung University’s Graduate Institute of Clinical Medical Sciences, wrote that the peptide might be produced by stomach microbes, as its amino acid sequence doesn’t appear in the human genome. Sara Talpos — Undark, STAT, 3 Feb. 2026 See All Example Sentences for genome

Word History

Etymology

German Genom, from Gen gene + -om (as in Chromosom chromosome)

First Known Use

1926, in the meaning defined above

Time Traveler
The first known use of genome was in 1926

Browse Nearby Words

Cite this Entry

“Genome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/genome. Accessed 8 Feb. 2026.

Medical Definition

genome

noun
ge·​nome ˈjē-ˌnōm How to pronounce genome (audio)
: one haploid set of chromosomes with the genes they contain
broadly : the genetic material of an organism
The idea behind sequencing an organism's genome—decoding, letter by letter, the message contained in every last one of its genes—is that it would tell us a lot about how the organism works. Lori Oliwenstein, Discover

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